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TIMP2 Polyklonaler Antikörper

TIMP2 Polyklonal Antikörper für IHC,ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IHC,ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 26647-1-AP

Synonyme

CSC 21K, Metalloproteinase inhibitor 2, TIMP 2, TIMP2

Galerie der Validierungsdaten

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  • Immunohistochemistry (IHC) staining of mouse lung tissue using TIMP2 Polyclonal antibody (26647-1-AP)

    IHC staining of mouse lung using 26647-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using 26647-1-AP (TIMP2 Antibody) at dilution of 1:200 (under 10x lens).

  • Immunohistochemistry (IHC) staining of mouse lung tissue using TIMP2 Polyclonal antibody (26647-1-AP)

    IHC staining of mouse lung using 26647-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using 26647-1-AP (TIMP2 Antibody) at dilution of 1:200 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human kidney tissue using TIMP2 Polyclonal antibody (26647-1-AP)

    IHC staining of human kidney using 26647-1-AP

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 26647-1-AP (TIMP2 Antibody) at dilution of 1:200 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human kidney tissue using TIMP2 Polyclonal antibody (26647-1-AP)

    IHC staining of human kidney using 26647-1-AP

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 26647-1-AP (TIMP2 Antibody) at dilution of 1:200 (under 40x lens).

Geprüfte Anwendungen

Erfolgreiche Detektion in IHCMauslungengewebe, humanes Nierengewebe
Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

AnwendungVerdünnung
Immunhistochemie (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

26647-1-AP bindet in IHC,ELISA TIMP2 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TIMP2 fusion protein Ag24436
Vollständiger Name TIMP metallopeptidase inhibitor 2
Berechnetes Molekulargewicht 220 aa, 24 kDa
GenBank-ZugangsnummerBC052605
Gene symbol TIMP2
Gene ID (NCBI) 7077
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The TIMPs are natural highly specific endogenous inhibitors of MMPs. Human TIMP family consists of four 21-28 kDa proteins known as TIMP1, TIMP2, TIMP3, and TIMP4 encoded by four paralogous genes.TIMPs are vital to the maintenance of ECM homeostasis primarily through their MMP inhibitory functions. TIMP2, a member of the TIMP family, regulates the proteolytic activity of all MMPs and is involved in cell differentiation, growth, migration, angiogenesis, and apoptosis. Urinary TIMP2 has been recently recognized as an early biomarker to predict Acute kidney injury (AKI) in critically ill patients.

Protokolle

Produktspezifische Protokolle
IHC protocol for TIMP2 antibody 26647-1-APProtokoll herunterladen
Standard-Protokolle
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen