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  • KD/KO Validated

SOX5 Polyklonaler Antikörper

SOX5 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus und mehr (1)

Anwendung

WB, IF, IHC, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13216-1-AP

Synonyme

L SOX5, SOX5, Transcription factor SOX 5



Geprüfte Anwendungen

Erfolgreiche Detektion in WBA549-Zellen, Mauslebergewebe, SH-SY5Y-Zellen, U-87 MG-Zellen

Empfohlene Verdünnung

AnwendungVerdünnung
Western Blot (WB)WB : 1:2000-1:10000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

13216-1-AP bindet in WB, IF, IHC, ELISA SOX5 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
In Publikationen genannte Reaktivitäthuman, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SOX5 fusion protein Ag4092
Vollständiger Name SRY (sex determining region Y)-box 5
Berechnetes Molekulargewicht 763 aa, 84 kDa
Beobachtetes Molekulargewicht 68-70 kDa
GenBank-ZugangsnummerBC029220
Gene symbol SOX5
Gene ID (NCBI) 6660
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Sex determining region Y-box protein 5 (SOX5) is a member of the SOX family, which was identified based on the conserved homology of the high-mobility group DNA-binding motif. It has been reported that SOX5 is involved in the regulation of embryonic development, and is associated with various cancer types, including prostate cancer, glioblastoma, hepatocellular carcinoma, osteosarcoma and nasopharyngeal carcinoma. SOX5 has 5 isoforms with the molecular mass of 42, 71 and 82-84 kDa. (PMID: 30854049)

Protokolle

Produktspezifische Protokolle
WB protocol for SOX5 antibody 13216-1-APProtokoll herunterladen
Standard-Protokolle
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
mouseWB

Nat Commun

VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination.

Authors - Yuki Miyamoto
mouse,ratWB

Pharmacol Res

Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviates ischemic/reperfusion brain injury via JUNB/JNK/NF-κB and SOX5/PI3K/AKT pathways.

Authors - Jiale Cai
humanWB,IHC

Cell Oncol (Dordr)

Apatinib inhibits glycolysis by suppressing the VEGFR2/AKT1/SOX5/GLUT4 signaling pathway in ovarian cancer cells.

Authors - Lihua Chen
  • KD Validated
humanWB

Phytomedicine

Transcriptomics, molecular docking, and cross-resistance profiling of nobiletin in cancer cells and synergistic interaction with doxorubicin upon SOX5 transfection.

Authors - Aveen N Adham
  • KO Validated
humanWB

Lab Invest

Sox13 promotes hepatocellular carcinoma metastasis by transcriptionally activating Twist1.

Authors - Min Feng
mouseIF

Mol Cell Biochem

Expression profiles of Sox transcription factors within the postnatal rodent testes.

Authors - Pauline Roumaud