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RACGAP1 Polyklonaler Antikörper

RACGAP1 Polyklonal Antikörper für WB, IP, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IP, IF, IHC, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13739-1-AP

Synonyme

HsCYK 4, ID GAP, KIAA1478, Male germ cell RacGap, MgcRacGAP, RACGAP1



Geprüfte Anwendungen

Erfolgreiche Detektion in WBK-562-Zellen, HeLa-Zellen, Maushodengewebe, RAW 264.7-Zellen
Erfolgreiche IPMaushodengewebe, HeLa-Zellen

Empfohlene Verdünnung

AnwendungVerdünnung
Western Blot (WB)WB : 1:500-1:1000
Immunpräzipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

13739-1-AP bindet in WB, IP, IF, IHC, ELISA RACGAP1 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
In Publikationen genannte Reaktivitäthuman, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen RACGAP1 fusion protein Ag4676
Vollständiger Name Rac GTPase activating protein 1
Berechnetes Molekulargewicht 632 aa, 71 kDa
Beobachtetes Molekulargewicht 71 kDa
GenBank-ZugangsnummerBC032754
Gene symbol RACGAP1
Gene ID (NCBI) 29127
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Rac GTPase-activating protein 1 (RACGAP1), localized in the mitotic spindle, has guanosine triphosphatase-activating protein (GAP) activity for the Rho family GTPases. RACGAP1 has an important influence on the initiation of cytokinesis, control of cell growth and differentiation, regulation of spermatogenesis, and tumor metastasis.

Protokolle

Produktspezifische Protokolle
WB protocol for RACGAP1 antibody 13739-1-APProtokoll herunterladen
IP protocol for RACGAP1 antibody 13739-1-APProtokoll herunterladen
Standard-Protokolle
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
humanWB,IHC

Front Cell Dev Biol

PRC1 and RACGAP1 are Diagnostic Biomarkers of Early HCC and PRC1 Drives Self-Renewal of Liver Cancer Stem Cells.

Authors - Shixin Liao
mouseWB,IHC

Front Pharmacol

Effects of Shenkang Pills on Early-Stage Diabetic Nephropathy in db/db Mice via Inhibiting AURKB/RacGAP1/RhoA Signaling Pathway.

Authors - Fujing Wang
mouseIF

Mol Biol Cell

Chromokinesin Kif4 promotes proper anaphase in mouse oocyte meiosis.

Authors - Carissa M Heath
humanWB,IHC

Cancers (Basel)

Lambda-Carrageenan Enhances the Effects of Radiation Therapy in Cancer Treatment by Suppressing Cancer Cell Invasion and Metastasis through Racgap1 Inhibition.

Authors - Ping-Hsiu Wu
humanWB

Cell Death Dis

Pseudogene RACGAP1P activates RACGAP1/Rho/ERK signalling axis as a competing endogenous RNA to promote hepatocellular carcinoma early recurrence.

Authors - Meng-Yao Wang
humanWB,IHC,IF

Cell Death Dis

PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling

Authors - Hualin Chen