• Überblick
  • Geprüfte Anwendungen
  • Produktinformation
  • Publikationen (27)
  • Protokolle
  • Rezensionen (1)
  • Featured Product
  • KD/KO Validated

PRDX3 Polyklonaler Antikörper

PRDX3 Polyklonal Antikörper für WB, IHC, IF/ICC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF/ICC, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 10664-1-AP

Synonyme

peroxiredoxin 3, MER5, EC:1.11.1.24, AOP-1, AOP1



Geprüfte Anwendungen

Erfolgreiche Detektion in WBHeLa-Zellen, HEK-293-Zellen, LNCaP-Zellen, Mausherzgewebe, Maushirngewebe, MCF-7-Zellen
Erfolgreiche Detektion in IHChumanes Lungenkarzinomgewebe
Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.
Erfolgreiche Detektion in IF/ICCHepG2-Zellen

Empfohlene Verdünnung

AnwendungVerdünnung
Western Blot (WB)WB : 1:2000-1:16000
Immunhistochemie (IHC)IHC : 1:50-1:500
Immunfluoreszenz (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

10664-1-AP bindet in WB, IHC, IF/ICC, ELISA PRDX3 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
In Publikationen genannte Reaktivitäthuman, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen PRDX3 fusion protein Ag1062
Vollständiger Name peroxiredoxin 3
Berechnetes Molekulargewicht 27 kDa
Beobachtetes Molekulargewicht 26-28 kDa
GenBank-ZugangsnummerBC007062
Gene symbol PRDX3
Gene ID (NCBI) 10935
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PRDX3(Peroxiredoxin 3), also named as AOP1, HBC189 and MER5, belongs to the ahpC/TSA family. It is involved in redox regulation of the cell and protects radical-sensitive enzymes from oxidative damage by a radical-generating system. PRDX3 is required for MYC-mediated proliferation, transformation, and apoptosis after glucose withdrawal and essential for maintaining mitochondrial mass and membrane potential in transformed rat and human cells (PMID:12011429). PRDX3 acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.

Protokolle

Produktspezifische Protokolle
WB protocol for PRDX3 antibody 10664-1-APProtokoll herunterladen
IHC protocol for PRDX3 antibody 10664-1-APProtokoll herunterladen
IF protocol for PRDX3 antibody 10664-1-APProtokoll herunterladen
Standard-Protokolle
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

  • Journal Impact Factor
  • Most recent
SpeciesApplicationTitle
mouseWB

Redox Biol

PMID: 32604037

Authors - Anindya Roy Chowdhury
humanWB,IHC

Redox Biol

LRPPRC regulates redox homeostasis via the circANKHD1/FOXM1 axis to enhance bladder urothelial carcinoma tumorigenesis.

Authors - Wen-Su Wei
humanWB

Redox Biol

Icariin alleviates uveitis by targeting peroxiredoxin 3 to modulate retinal microglia M1/M2 phenotypic polarization.

Authors - Guoqing Wang
  • KD Validated
ratIF

Oxid Med Cell Longev

Paeoniflorin Upregulates Mitochondrial Thioredoxin of Schwann Cells to Improve Diabetic Peripheral Neuropathy Indicated by 4D Label-Free Quantitative Proteomics.

Authors - Xinwei Yang
humanWB

Mol Cell Proteomics

Proteomics characterization of the cytotoxicity mechanism of ganoderic acid D and computer-automated estimation of the possible drug target network.

Authors - Yue Qing-Xi QX

J Clin Endocrinol Metab

Thioredoxin reductase 2 (TXNRD2) mutation associated with familial glucocorticoid deficiency (FGD).

Authors - Rathi Prasad

Rezensionen

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.


FH

Guillermo (Verified Customer) (09-03-2022)

I trust in Proteintech, my favourite antibody company. 5/5 product.

  • Applications: Western Blot

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