PLSCR4 Polyklonaler Antikörper

PLSCR4 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Publikationen

1

Kat-Nr. : 12630-1-AP

Synonyme

phospholipid scramblase 4, PL scramblase 4, PLSCR4, TRA1

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Galerie der Validierungsdaten

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  WB analysis of human heart using 12630-1-AP

  human heart tissue were subjected to SDS PAGE followed by western blot with 12630-1-AP (PLSCR4 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

• 

  WB analysis of human brain using 12630-1-AP

  human brain tissue were subjected to SDS PAGE followed by western blot with 12630-1-AP (PLSCR4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse testis using 12630-1-AP

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 12630-1-AP (PLSCR4 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

• 

  WB analysis of human placenta using 12630-1-AP

  human placenta tissue were subjected to SDS PAGE followed by western blot with 12630-1-AP (PLSCR4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

• 

  WB analysis of human liver using 12630-1-AP

  human liver tissue were subjected to SDS PAGE followed by western blot with 12630-1-AP (PLSCR4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: humanes Herzgewebe, humanes Hirngewebe, humanes Lebergewebe, humanes Plazenta-Gewebe, Maushodengewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:3000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 1 publications below

Produktinformation

12630-1-AP bindet in WB, ELISA PLSCR4 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: PLSCR4 fusion protein Ag3323
• Vollständiger Name: phospholipid scramblase 4
• Berechnetes Molekulargewicht: 329 aa, 37 kDa
• Beobachtetes Molekulargewicht: 37 kDa
• GenBank-Zugangsnummer: BC028354
• Gene symbol: PLSCR4
• Gene ID (NCBI): 57088
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PLSCR4 (Phospholipid scramblase 4) belongs to the phospholipid scramblase family which is thought to mediate the loss of lipid asymmetry. Elimination of this lipid bilayer asymmetry is an important physiological process and appears to occur as a result of elevated intracellular calcium concentration, or occur with cell activation, injury, and apoptosis.PLSCR4 also plays a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.

Publikationen

Species	Application	Title
mouse	WB	Reprod Sci; Phospholipid scramblase expression in the pregnant mouse uterus in LPS-induced preterm delivery.; Authors - McLean Kelley C KC