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PAX8 Polyklonaler Antikörper

PAX8 Polyklonal Antikörper für WB,ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB,ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 22255-1-AP

Synonyme

paired box 8, Paired box protein Pax 8, PAX8

Galerie der Validierungsdaten

Filter:
  • Western Blot (WB) analysis of A2780 cells using PAX8 Polyclonal antibody (22255-1-AP)

    WB analysis of A2780 using 22255-1-AP

    A2780 cells were subjected to SDS PAGE followed by western blot with 22255-1-AP (PAX8 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

  • Western Blot (WB) analysis of A2780 cells using PAX8 Polyclonal antibody (22255-1-AP)

    WB analysis of A2780 using 22255-1-AP

    A2780 cells were subjected to SDS PAGE followed by western blot with 22255-1-AP (PAX8 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human ovary tumor using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 22255-1-AP (PAX8 antibody) at dilution of 1:100 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human ovary tumor using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 22255-1-AP (PAX8 antibody) at dilution of 1:100 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human ovary tumor using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 22255-1-AP (PAX8 antibody) at dilution of 1:10 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human ovary tumor using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 22255-1-AP (PAX8 antibody) at dilution of 1:50 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human ovary tumor using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 22255-1-AP (PAX8 antibody) at dilution of 1:50 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human ovary tumor using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 22255-1-AP (PAX8 antibody) at dilution of 1:25 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human ovary tumor using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 22255-1-AP (PAX8 antibody) at dilution of 1:25 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human ovary tumor using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 22255-1-AP (PAX8 antibody) at dilution of 1:10 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human ovary tumor using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 22255-1-AP (PAX8 antibody) at dilution of 1:10 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human ovary tumor using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 22255-1-AP (PAX8 antibody) at dilution of 1:10 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human ovary tumor using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 22255-1-AP (PAX8 antibody) at dilution of 1:25 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human ovary tumor using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 22255-1-AP (PAX8 antibody) at dilution of 1:25 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human ovary tumor using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 22255-1-AP (PAX8 antibody) at dilution of 1:50 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human ovary tumor using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 22255-1-AP (PAX8 antibody) at dilution of 1:50 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human ovary tumor using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 22255-1-AP (PAX8 antibody) at dilution of 1:50 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human ovary tumor using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 22255-1-AP (PAX8 antibody) at dilution of 1:50 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human kidney tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human kidney using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human kidney using 22255-1-AP (PAX8 antibody) at dilution of 1:50 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human kidney tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human kidney using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human kidney using 22255-1-AP (PAX8 antibody) at dilution of 1:50 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human ovary tumor using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 22255-1-AP (PAX8 antibody) at dilution of 1:50 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human ovary tumor using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 22255-1-AP (PAX8 antibody) at dilution of 1:50 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human ovary tumor using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 22255-1-AP (PAX8 antibody) at dilution of 1:50 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using PAX8 Polyclonal antibody (22255-1-AP)

    IHC staining of human ovary tumor using 22255-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 22255-1-AP (PAX8 antibody) at dilution of 1:50 (under 40x lens).

Geprüfte Anwendungen

Empfohlene Verdünnung

AnwendungVerdünnung
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

22255-1-AP bindet in WB,ELISA PAX8 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen PAX8 fusion protein Ag17759
Vollständiger Name paired box 8
Berechnetes Molekulargewicht 450 aa, 48 kDa
GenBank-ZugangsnummerBC001060
Gene symbol PAX8
Gene ID (NCBI) 7849
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PAX8 is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain and a paired-type homeodomain. It is expressed during organogenesis of the thyroid gland, kidney and Mullerian system. It is thought to regulate the expression of Wilms tumor suppressor (WT1) gene and mutations in PAX8 have been associated with Wilms tumor cells, thyroid and ovarian carcinomas. PAX8 is a useful marker in distinguishing ovarian carcinomas from mammary carcinomas (PMID: 18724243). PAX8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas.

PAX8 has 5 isoforms with calculated MW 31kd, 34kd, 41kd, 43kd and 48kd. And there is a 60kd band corresponding to the electrophoretic mobility of PAX8 (PMID:15650356). Proteintech’s 10336-1-AP antibody has cross-reactivities with the other PAX family members.