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NRG4 Polyklonaler Antikörper

NRG4 Polyklonal Antikörper für IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IHC, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 11206-1-AP

Synonyme

HRG4, neuregulin 4, NRG 4, NRG4, Pro NRG4

Galerie der Validierungsdaten

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  • Immunohistochemistry (IHC) staining of human breast cancer tissue using NRG4 Polyclonal antibody (11206-1-AP)

    IHC staining of human breast cancer using 11206-1-AP

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 11206-1-AP (NRG4 Antibody) at dilution of 1:50 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human breast cancer tissue using NRG4 Polyclonal antibody (11206-1-AP)

    IHC staining of human breast cancer using 11206-1-AP

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 11206-1-AP (NRG4 Antibody) at dilution of 1:50 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human prostate cancer tissue using NRG4 Polyclonal antibody (11206-1-AP)

    IHC staining of human prostate cancer using 11206-1-AP

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 11206-1-AP (NRG4 Antibody) at dilution of 1:50 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human prostate cancer tissue using NRG4 Polyclonal antibody (11206-1-AP)

    IHC staining of human prostate cancer using 11206-1-AP

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 11206-1-AP (NRG4 Antibody) at dilution of 1:50 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using NRG4 Polyclonal antibody (11206-1-AP)

    IHC staining of human ovary tumor using 11206-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 11206-1-AP (NRG4 antibody) at dilution of 1:50 (under 40x lens).

Geprüfte Anwendungen

Erfolgreiche Detektion in IHChumanes Mammakarzinomgewebe, humanes Ovarialkarzinomgewebe, humanes Prostatakarzinomgewebe
Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

AnwendungVerdünnung
Immunhistochemie (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

11206-1-AP bindet in IHC, ELISA NRG4 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen NRG4 fusion protein Ag1697
Vollständiger Name neuregulin 4
Berechnetes Molekulargewicht 13 kDa
GenBank-ZugangsnummerBC017568
Gene symbol NRG4
Gene ID (NCBI) 145957
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Neuregulin 4 (Nrg4), a member of the epidermal growth factor (EGF) family of extracellular ligands, is expressed in multiple organs with the highest expression levels in brown adipose tissue. Neuregulin 4 is a secreted adipokine recently identified as playing an important role in modulating systemic energy metabolism and in the development of metabolic disorders in rodent and human obesity, including type 2 diabetes and non-alcoholic fatty liver disease (NAFLD). Nrg4 attenuates hepatic lipogenic signaling and preserves glucose and lipid homeostasis in obesity.