Lamin B1 Monoklonaler Antikörper

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• KD/KO Validated

Lamin B1 Monoklonal Antikörper für WB

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB

Konjugation

HRP Fluorescent Dye

CloneNo.

3C10G12

Kat-Nr. : HRP-66095

Synonyme

ADLD, lamin B1, LMN, LMN2, LMNB, LMNB1

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Galerie der Validierungsdaten

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  WB analysis using HRP-66095

  Various lysates were subjected to SDS PAGE followed by western blot with HRP-66095 (Lamin B1 antibody) at dilution of 1:100000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HeLa-Zellen, PC-12-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:20000-1:100000

Sample-dependent, check data in validation data gallery

Produktinformation

HRP-66095 bindet in WB Lamin B1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Lamin B1 fusion protein Ag20522
• Vollständiger Name: lamin B1
• Berechnetes Molekulargewicht: 66 kDa
• Beobachtetes Molekulargewicht: 66-70 kDa
• GenBank-Zugangsnummer: BC012295
• Gene symbol: LMNB1
• Gene ID (NCBI): 4001
• Konjugation: HRP Fluorescent Dye
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: BS mit 50% Glyzerin, 0,05% Proclin300, 0,5% BSA, pH 7,3.
• Lagerungsbedingungen: Bei -20°C lagern. Vor Licht schützen. Nach dem Versand ein Jahr stabil. Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. This protein is not suitable for samples where the nuclear envelope has been removed.