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LSM2 Polyklonaler Antikörper

LSM2 Polyklonal Antikörper für WB, IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 10963-1-AP

Synonyme

C6orf28, G7b, LSM2, Protein G7b, snRNP, YBL026W

Galerie der Validierungsdaten

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  • Immunohistochemistry (IHC) staining of human lymphoma tissue using LSM2 Polyclonal antibody (10963-1-AP)

    IHC staining of human lymphoma using 10963-1-AP

    Immunohistochemical analysis of paraffin-embedded human lymphoma using 10963-1-AP (LSM2 antibody) at dilution of 1:50 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human lymphoma tissue using LSM2 Polyclonal antibody (10963-1-AP)

    IHC staining of human lymphoma using 10963-1-AP

    Immunohistochemical analysis of paraffin-embedded human lymphoma using 10963-1-AP (LSM2 antibody) at dilution of 1:50 (under 10x lens).

Geprüfte Anwendungen

Veröffentlichte Anwendungen

IHCSee 1 publications below

Produktinformation

10963-1-AP bindet in WB, IHC, ELISA LSM2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
In Publikationen genannte Reaktivitäthuman
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen LSM2 fusion protein Ag1412
Vollständiger Name LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Berechnetes Molekulargewicht 11 kDa
GenBank-ZugangsnummerBC009192
Gene symbol LSM2
Gene ID (NCBI) 57819
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family. Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing[PMID:15075370]. Lsm2–Lsm8 (Lsm stands for Like Sm), binds and stabilizes the 3′ end of the spliceosomal U6 snRNA Lsm proteins facilitate the annealing of U6 snRNA with U4 snRNA in vitro and interact with the U4/U6 annealing factor Prp24, suggesting that Lsm proteins function in U4/U6 snRNP formation in vivo [PMID:15485930, 17251193].

Publikationen

SpeciesApplicationTitle
humanIHC

J Proteomics

Low-molecular-mass secretome profiling identifies C-C motif chemokine 5 as a potential plasma biomarker and therapeutic target for nasopharyngeal carcinoma.

Authors - Lin Shih-Jie SJ
View Article