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IL-16 Polyklonaler Antikörper

IL-16 Polyklonal Antikörper für IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13352-1-AP

Synonyme

HsT19289, IL 16, IL16, IL-16, interleukin-16, LCF, prIL 16, Pro interleukin 16

Galerie der Validierungsdaten

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  • Immunohistochemistry (IHC) staining of human prostate cancer tissue using IL-16 Polyclonal antibody (13352-1-AP)

    IHC staining of human prostate cancer using 13352-1-AP

    Immunohistochemical analysis of paraffin-embedded human prostate cancer using 13352-1-AP (IL-16 antibody) at dilution of 1:100 (under 10x lens).

Geprüfte Anwendungen

Produktinformation

13352-1-AP bindet in IHC, ELISA IL-16 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen IL-16 fusion protein Ag4044
Vollständiger Name interleukin 16 (lymphocyte chemoattractant factor)
Berechnetes Molekulargewicht 130 aa, 15 kDa
GenBank-ZugangsnummerBC040272
Gene symbol IL-16
Gene ID (NCBI) 3603
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. It is mainly produced by T lymphocytes but also by other immune cells, neuronal cells, fibroblasts and epithelial cells. The signaling process of this cytokine is mediated by CD4. IL-16 induces chemotaxis of CD4+ cells such as lymphocytes, eosinophils, and dendritic cells by ligating CD4 directly at a site distinct from other ligands. Among its multiple functions, IL-16 is a T cell chemoattractant involved in T helper cell inflammatory responses and the regulation of both T cell growth, and responsiveness to regulatory cytokines. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control.