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IL15 Polyklonaler Antikörper

IL15 Polyklonal Antikörper für IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

IHC, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12962-1-AP

Synonyme

IL 15, IL15, interleukin 15

Galerie der Validierungsdaten

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  • Immunohistochemistry (IHC) staining of human lung cancer tissue using IL-15 Polyclonal antibody (12962-1-AP)

    IHC staining of human lung cancer using 12962-1-AP

    Immunohistochemical analysis of paraffin-embedded human lung cancer using 12962-1-AP (IL15 antibody) at dilution of 1:100 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human placenta tissue using IL-15 Polyclonal antibody (12962-1-AP)

    IHC staining of human placenta using 12962-1-AP

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 12962-1-AP (IL15 Antibody) at dilution of 1:50 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human placenta tissue using IL-15 Polyclonal antibody (12962-1-AP)

    IHC staining of human placenta using 12962-1-AP

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 12962-1-AP (IL15 Antibody) at dilution of 1:50 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human testis tissue using IL-15 Polyclonal antibody (12962-1-AP)

    IHC staining of human testis using 12962-1-AP

    Immunohistochemical analysis of paraffin-embedded human testis tissue slide using 12962-1-AP (IL15 Antibody) at dilution of 1:50 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human testis tissue using IL-15 Polyclonal antibody (12962-1-AP)

    IHC staining of human testis using 12962-1-AP

    Immunohistochemical analysis of paraffin-embedded human testis tissue slide using 12962-1-AP (IL15 Antibody) at dilution of 1:50 (under 40x lens).

Geprüfte Anwendungen

Produktinformation

12962-1-AP bindet in IHC, ELISA IL15 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen IL15 fusion protein Ag3650
Vollständiger Name interleukin 15
Berechnetes Molekulargewicht 18 kDa
GenBank-ZugangsnummerBC018149
Gene symbol IL15
Gene ID (NCBI) 3600
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Interleukin 15 (IL15) is a cytokine important for the development, maturation, and function of many cells of the immune system including NK, NKT, gammadeltaT, and CD8(+) T cells. Its expression affects homeostasis and function of B cells through NK cell-derived IFNG. IL-15 binds a trimeric IL-15 receptor (IL-15R) complex formed by a specific receptor chain (IL-15Rα) combined with theβandγchains of the IL-2R, acting as signal transducing components. High levels of IL15 expression have been associated with the pathogenesis of autoimmune and inflammatory diseases like Crohn’s disease, psoriasis, leukemias, rheumatoid arthritis (RA) and graft rejection, resulting in the IL15 system being a target of interest for the treatment of these diseases.