NeutraKine®HGF Monoklonaler Antikörper
NeutraKine®HGF Monoklonal Antikörper für Neutralization, ELISA
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
human
Anwendung
Neutralization, ELISA
Konjugation
Unkonjugiert
CloneNo.
2D2B4
Kat-Nr. : 69027-1-Ig
Synonyme
Galerie der Validierungsdaten
Neutralization |
Produktinformation
69027-1-Ig bindet in Neutralization, ELISA NeutraKine®HGF und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Maus / IgG1 |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | human HumankineHGF protein HZ-1084 |
Vollständiger Name | hepatocyte growth factor (hepapoietin A; scatter factor) |
Gene symbol | HGF |
Gene ID (NCBI) | 3082 |
Konjugation | Unkonjugiert |
Form | Lyophilized Powder |
Reinigungsmethode | Protein-G-Reinigung |
Lagerungspuffer | Sterile PBS. |
Endotoxin | <0.1 EU/μg |
Wiederherstellung | This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use. |
Stability and Storage | Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products. |
Hintergrundinformationen
Hepatocyte growth factor (HGF) is the most potent mitogen of mature hepatocytes in primary culture. HGF is derived from a biologically inactive single chain precursor of 728 amino acids (pro-HGF) localized mostly on the cell surface and in the extracellular matrix. The mature form produced following proteolytic cleavage is composed of a 69-kDa α-subunit (containing four kringle domains) and the 34 kDa β-subunit, similar to the catalytic domain of serine proteases, but with amino acid substitutions in the active site. HGF is a pleiotropic cytokine which exerts a variety of effects on several cells, being involved in the regulation of many biological processes, such as inflammation, tissue repair, morphogenesis, angiogenesis, tumour propagation, immunomodulation of viral infections and cardio-metabolic activities.
This antibody is used to neutralize the bioactivity of HGF.