• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

GCGR Rekombinanter Antikörper

GCGR Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241501C4

Kat-Nr. : 84237-5-PBS

Synonyme

glucagon receptor, GL-R, GL R, GGR, 241501C4

Filter:
  • Western Blot (WB) analysis of various lysates using GCGR Recombinant antibody (84237-5-RR)

    WB analysis using 84237-5-RR (same clone as 84237-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84237-5-RR (GCGR antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84237-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84237-5-RR

    Affinity and Kinetic Characterization of 84237-5-RR

    Biolayer interferometry (BLl) kinetic assays of 84237-5-RR against Human GCGR were performed. The affinity constant is 71.6 pM.

Geprüfte Anwendungen

Produktinformation

84237-5-PBS bindet in WB, Indirect ELISA GCGR und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen GCGR fusion protein Ag24861
Vollständiger Name glucagon receptor
Berechnetes Molekulargewicht 477 aa, 54 kDa
Beobachtetes Molekulargewicht62-68 kDa
GenBank-ZugangsnummerBC104854
Gene symbol GCGR
Gene ID (NCBI) 2642
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Glucagon receptor (GCGR) is a secretin-like (class B) family of G-protein coupled receptors (GPCRs). It plays an important role in elevating the glucose concentration in the blood and has thus become one of the promising therapeutic targets for treating type 2 diabetes mellitus (PMID: 26236379). GCGR is a 62-kDa glycoprotein that contains at least four N-linked oligosaccharide chains (PMID: 2174441; 15245877). Defects in the gene of GCGR cause non-insulin-dependent diabetes mellitus (NIDDM).