DPP3 Polyklonaler Antikörper

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• KD/KO Validated

DPP3 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Publikationen

3

Kat-Nr. : 10650-1-AP

Synonyme

Dipeptidyl aminopeptidase III, Dipeptidyl arylamidase III, dipeptidyl peptidase 3, Dipeptidyl peptidase III, DPP III, DPP3, DPPIII

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Galerie der Validierungsdaten

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  WB analysis of mouse thymus using 10650-1-AP

  mouse thymus tissue were subjected to SDS PAGE followed by western blot with 10650-1-AP (DPP3 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse thymus using 10650-1-AP

  mouse thymus tissue were subjected to SDS PAGE followed by western blot with 10650-1-AP (DPP3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of human placenta using 10650-1-AP

  human placenta tissue were subjected to SDS PAGE followed by western blot with 10650-1-AP (DPP3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse thymus using 10650-1-AP

  mouse thymus tissue were subjected to SDS PAGE followed by western blot with 10650-1-AP (DPP3 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Maus-Thymusgewebe, humanes Plazenta-Gewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 1 publications below
• WB: See 3 publications below

Produktinformation

10650-1-AP bindet in WB, ELISA DPP3 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: DPP3 fusion protein Ag1022
• Vollständiger Name: dipeptidyl-peptidase 3
• Berechnetes Molekulargewicht: 83 kDa
• Beobachtetes Molekulargewicht: 69 kDa, 83 kDa
• GenBank-Zugangsnummer: BC007221
• Gene symbol: DPP3
• Gene ID (NCBI): 10072
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

DPP3 (dipeptidyl-peptidase 3), also known as DPPIII, is one of the dipeptidyl aminopeptidases, that belongs to the peptidase M49 family. DPP3 is a metalloenzyme containing one Zn2+ ion in its active site. Furthermore, It was shown to have a novel zinc-binding motif ( HELLGH). DPP3 has been reported as an important enkephalin-degrading enzyme in the central nervous system, in human neutrophils.It has 3 isoforms produced by alternative splicing. Increased activity of DPP3 is associated with endometrial and ovarian cancers.

Publikationen

Species	Application	Title
mouse	WB	J Biol Chem; Dipeptidyl peptidase 3 modulates the renin-angiotensin system in mice.; Authors - Shalinee Jha ; KO Validated
mouse	WB	Environ Mol Mutagen; Proteomic biomarkers for prenatal bisphenol A-exposure in mouse immune organs.; Authors - Yang Mihi M
mouse	WB	Int Immunopharmacol; Dipeptidyl peptidase 3 is essential for maintaining osteoblastic differentiation under a high-glucose environment by inhibiting apoptosis, oxidative stress and inflammation through the modulation of the Keap1-Nrf2 pathway; Authors - Xiaofeng Li