CXCL16 Polyklonaler Antikörper
CXCL16 Polyklonal Antikörper für ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human und mehr (1)
Anwendung
WB, IHC, ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 13902-1-AP
Synonyme
Galerie der Validierungsdaten
Geprüfte Anwendungen
Veröffentlichte Anwendungen
WB | See 1 publications below |
IHC | See 3 publications below |
Produktinformation
13902-1-AP bindet in WB, IHC, ELISA CXCL16 und zeigt Reaktivität mit human
Getestete Reaktivität | human |
In Publikationen genannte Reaktivität | human, Maus |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Polyklonal |
Typ | Antikörper |
Immunogen | CXCL16 fusion protein Ag4872 |
Vollständiger Name | chemokine (C-X-C motif) ligand 16 |
Berechnetes Molekulargewicht | 273 aa, 30 kDa |
GenBank-Zugangsnummer | BC017588 |
Gene symbol | CXCL16 |
Gene ID (NCBI) | 58191 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Antigen-Affinitätsreinigung |
Lagerungspuffer | PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3. |
Lagerungsbedingungen | Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
CXCL16 is a recently discovered cytokine belonging to the CXC chemokine family, which is synthesised in plasmacytoid dendritic cell as a transmembrane molecule. It exists in a transmembrane and soluble form. The transmembrane form of CXCL16 functions as an adhesion molecule for CXCR6-expressing cells, whereas the soluble form of CXCL16 mediates infiltration of circulating cells into sites of injury. CXCL16, has been proposed as an important pathogenic mediator in inflammatory diseases, including rheumatoid arthritis, glomerulonephritis, or prostate cancer. CXCL16 has been implicated in some forms of renal disease such as lupus nephritis and antiglomerular basement membrane nephritis. CXCL16 also plays a pivotal role in the pathogenesis of angiotensin II-induced renal injury and fibrosis through regulation of macrophage and T cell infiltration and bone marrow-derived fibroblast accumulation.
Publikationen
Species | Application | Title |
---|---|---|
Pathol Res Pract OVOL2 attenuates the expression of MAP3K8 to suppress epithelial mesenchymal transition in colorectal cancer. | ||
J Viral Hepat Serum CXCL16: A new predictor of liver inflammation in patients with chronic hepatitis B | ||
Transl Oncol CXCL16 promotes tumor metastasis by regulating angiogenesis in the tumor micro-environment of BRAF V600E mutant colorectal cancer |