hCG Beta Polyklonaler Antikörper

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• KD/KO Validated

hCG Beta Polyklonal Antikörper für IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF, IHC, ELISA

Konjugation

Unkonjugiert

Publikationen

9

Kat-Nr. : 11615-1-AP

Synonyme

CG beta, CGB, CGB3, CGB5, CGB7, CGB8, hCG, hCGB

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Galerie der Validierungsdaten

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  IHC staining of human placenta using 11615-1-AP

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 11615-1-AP (hCG beta antibody at dilution of 1:200 (under 10x lens).

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  IHC staining of human placenta using 11615-1-AP

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 11615-1-AP (hCG beta antibody at dilution of 1:200 (under 40x lens).

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  IHC staining of human placenta using 11615-1-AP

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 11615-1-AP (hCG beta antibody at dilution of 1:200 (under 10x lens).

• 

  IHC staining of human placenta using 11615-1-AP

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 11615-1-AP (hCG beta antibody at dilution of 1:200 (under 40x lens).

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  IHC staining of human breast cancer using 11615-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 11615-1-AP (hCG beta antibody at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human breast cancer using 11615-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 11615-1-AP (hCG beta antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Geprüfte Anwendungen

• Erfolgreiche Detektion in IHC: humanes Plazenta-Gewebe, humanes Mammakarzinomgewebe; Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

• Immunhistochemie (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 1 publications below
• WB: See 8 publications below
• IF: See 2 publications below

Produktinformation

11615-1-AP bindet in WB, IF, IHC, ELISA hCG Beta und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: hCG Beta fusion protein Ag2191
• Vollständiger Name: CG beta
• Berechnetes Molekulargewicht: 165 aa, 18 kDa
• GenBank-Zugangsnummer: BC022796
• Gene symbol: hCG Beta
• Gene ID (NCBI): 1082
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CGB is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of CG. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.

Publikationen

Species	Application	Title
human	IF	EBioMedicine; Molecular mechanisms underlying altered neurobehavioural development of female offspring of mothers with polycystic ovary syndrome: FOS-mediated regulation of neurotrophins in placenta.; Authors - Fangfang Wang
human	WB	Mol Cell Endocrinol; Activation of G protein-coupled estrogen receptor stimulates placental human chorionic gonadotropin expression through PKA-CREB signaling; Authors - Sizhu Yang
human	WB	Biomolecules; Calnexin Is Involved in Forskolin-Induced Syncytialization in Cytotrophoblast Model BeWo Cells; Authors - Hitomi Matsukawa
human	WB,IF	Mol Hum Reprod; The roles of ADAMDEC1 in trophoblast differentiation during normal pregnancy and preeclampsia.; Authors - Zhuo-Hang Li
human	WB	Placenta; Amphiregulin stimulates human chorionic gonadotropin expression by inducing ERK1/2-mediated ID3 expression in trophoblast cells.; Authors - Lanlan Fang
human	WB	Biol Trace Elem Res; PMID: 28983820; Authors - Mengdi Li ; KD Validated