CD45.2 Monoklonaler Antikörper

CD45.2 Monoklonal Antikörper für FC

Wirt / Isotyp

Maus / IgG2a, kappa

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

CoraLite® Plus 555 Fluorescent Dye

CloneNo.

104

Kat-Nr. : CL555-65072

Synonyme

B220, Cd45, CD45R, loc, Ly 5, Lyt 4, Ptprc, T200



Geprüfte Anwendungen

Erfolgreiche Detektion in FCC57BL/6 mouse splenocytes

Empfohlene Verdünnung

AnwendungVerdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

CL555-65072 bindet in FC CD45.2 und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Maus / IgG2a, kappa
Klonalität Monoklonal
Typ Antikörper
Immunogen B10.S-Maus-Thymozyten und -Splenozyten
Vollständiger Name protein tyrosine phosphatase, receptor type, C
GenBank-ZugangsnummerBC028512
Gene symbol Ptprc
Gene ID (NCBI) 19264
Konjugation CoraLite® Plus 555 Fluorescent Dye
Excitation/Emission maxima wavelengths554 nm / 570 nm
Form Liquid
Reinigungsmethode Affinitätsreinigung
Lagerungspuffer PBS with 0.09% sodium azide.
LagerungsbedingungenStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097). Allelic variants of mouse CD45, CD45.1 (Ly5.1) and CD45.2 (Ly5.1), have been established as a marker system to track haematopoietic cells following congenic mouse bone marrow transplants (PMID: 28615666). CD45.2 is the common form and is expressed by most of the established strains, while CD45.1 is found in only a few like the SJL mouse strain (PMID: 3489673).

Protokolle

Produktspezifische Protokolle
FC protocol for CL Plus 555 CD45.2 antibody CL555-65072Protokoll herunterladen
Standard-Protokolle
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen