CD39/ENTPD1 Monoklonaler Antikörper
CD39/ENTPD1 Monoklonal Antikörper für
Wirt / Isotyp
Maus / IgG2a
Getestete Reaktivität
human
Anwendung
Konjugation
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
2D2H6
Kat-Nr. : CL488-60323
Synonyme
Geprüfte Anwendungen
Produktinformation
CL488-60323 bindet in CD39/ENTPD1 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Maus / IgG2a |
| Klonalität | Monoklonal |
| Typ | Antikörper |
| Immunogen | CD39/ENTPD1 fusion protein Ag6165 |
| Vollständiger Name | ectonucleoside triphosphate diphosphohydrolase 1 |
| Berechnetes Molekulargewicht | 58 kDa |
| Beobachtetes Molekulargewicht | 54 kDa |
| GenBank-Zugangsnummer | BC047664 |
| Gene symbol | CD39 |
| Gene ID (NCBI) | 953 |
| Konjugation | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Reinigungsmethode | Protein-A-Reinigung |
| Lagerungspuffer | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA |
| Lagerungsbedingungen | Bei -20°C lagern. Vor Licht schützen. Nach dem Versand ein Jahr stabil. Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
ENTPD1(Ectonucleoside triphosphate diphosphohydrolase 1) is also named CD39, NTPDase 1, and Ecto-ATPDase 1 and belongs to the GDA1/CD39 NTPase family. In the nervous system, it can hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. It is a noncovalent tetrameric protein and detergent inhibition of enzymatic activity is caused by dissociation of ectoapyrase tetramers into monomers(PMID: 9733785 ). And it is a 70- to 100-kDa protein that is heavily N-glycosylated(PMID:7930580). This protein has 6 glycosylation sites and 3 isoforms(58 kDa, 59 kDa, and 34 kDa) produced by alternative splicing. The soluble isoform of CD39(38-478 amino acid) is located in the extracellular part and 60323-1-Ig can recognize the soluble form of CD39 (38-478aa) molecule.
