ABL2 Monoklonaler Antikörper
ABL2 Monoklonal Antikörper für WB,ELISA
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
human
Anwendung
WB,ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 65041-1-Ig
Synonyme
Galerie der Validierungsdaten
Geprüfte Anwendungen
| Erfolgreiche Detektion in WB | Human brain |
Empfohlene Verdünnung
| Anwendung | Verdünnung |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Produktinformation
65041-1-Ig bindet in WB,ELISA ABL2 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Maus / IgG1 |
| Klonalität | Monoklonal |
| Typ | Antikörper |
| Immunogen | Rekombinantes Protein |
| Vollständiger Name | v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) |
| Berechnetes Molekulargewicht | 1167 aa, 127 kDa |
| Beobachtetes Molekulargewicht | 128 kDa-140 kDa |
| GenBank-Zugangsnummer | BC065912 |
| Gene symbol | ABL2 |
| Gene ID (NCBI) | 27 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. |
| Lagerungsbedingungen | Bei 2-8℃ lagern. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
ABL2(Abelson tyrosine-protein kinase 2) is also named as ABLL, ARG and belongs to the protein kinase superfamily. It is a membrane-anchored nonreceptor tyrosine kinase that is a novel mediator of SEMA3F-induced RhoA inactivation and collapsing activity and it has a role in cytoskeletal rearrangements by its C-terminal F-actin- and microtubule-binding sequences. ABL2 can be polyubiquitinated and the polyubiquitination of ABL2 leads to degradation. This protein has 9 isoforms produced by alternative splicing with the molecular weight from 114 kDa to 128 kDa. The antibody is specific to the others except the 60 kDa isoform of ABL2.
