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CXCR2 Polyclonal antibody

CXCR2 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 19538-1-AP

Synonyms

Cxcr2-Specific, CXCR-2, CXC-R2, C-X-C chemokine receptor type 2, Cmkar2

Validation Data Gallery

Filter:
  • Immunohistochemistry (IHC) staining of mouse spleen tissue using CXCR2 Polyclonal antibody (19538-1-AP)

    IHC staining of mouse spleen using 19538-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse spleen tissue slide using 19538-1-AP (Il8rb-Specific antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunohistochemistry (IHC) staining of mouse spleen tissue using CXCR2 Polyclonal antibody (19538-1-AP)

    IHC staining of mouse spleen using 19538-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse spleen tissue slide using 19538-1-AP (Il8rb-Specific antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

Tested Applications

Positive IHC detected inmouse spleen tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

IHCSee 1 publications below

Product Information

19538-1-AP targets CXCR2 in IHC, ELISA applications and shows reactivity with mouse samples.

Tested Reactivity mouse
Cited Reactivitymouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name interleukin 8 receptor, beta
Calculated Molecular Weight 41 kDa
GenBank Accession NumberNM_009909
Gene Symbol Cxcr2
Gene ID (NCBI) 12765
RRIDAB_2878587
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Cmkar2, also named as Cxcr2, Gpcr16 and CD182, belongs to the G-protein coupled receptor 1 family. Il8rb is a receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Il8rb binds to IL-8 with high affinity. Il8rb also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. This antibody is specific to mouse Il8rb.

Protocols

Product Specific Protocols
IHC protocol for CXCR2 antibody 19538-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseIHC

Adv Sci (Weinh)

Tumor Microenvironment Responsive CD8+ T Cells and Myeloid-Derived Suppressor Cells to Trigger CD73 Inhibitor AB680-Based Synergistic Therapy for Pancreatic Cancer

Authors - Qiangda Chen
View Article