- Phare
- Validé par KD/KO
Anticorps Monoclonal anti-RND3
RND3 Monoclonal Antibody for WB,ELISA
Hôte / Isotype
Mouse / IgG2b
Réactivité testée
Humain, porc
Applications
WB, ELISA
Conjugaison
Non conjugué
CloneNo.
3H8F9
N° de cat : 66228-1-Ig
Synonymes
Galerie de données de validation
Applications testées
Résultats positifs en WB | tissu cérébral humain fœtal |
Dilution recommandée
Application | Dilution |
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Western Blot (WB) | WB : 1:1000-1:4000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Applications publiées
KD/KO | See 1 publications below |
WB | See 3 publications below |
Informations sur le produit
66228-1-Ig cible RND3 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, porc
Réactivité | Humain, porc |
Réactivité citée | Humain |
Hôte / Isotype | Mouse / IgG2b |
Clonalité | Monoclonal |
Type | Anticorps |
Immunogène | RND3 Protéine recombinante Ag18839 |
Nom complet | Rho family GTPase 3 |
Masse moléculaire calculée | 244 aa, 27 kDa |
Poids moléculaire observé | 29 kDa |
Numéro d’acquisition GenBank | BC012513 |
Symbole du gène | RND3 |
Identification du gène (NCBI) | 390 |
Conjugaison | Non conjugué |
Forme | Liquide |
Méthode de purification | Purification par protéine A |
Tampon de stockage | PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3 |
Conditions de stockage | Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. |
Informations générales
Rnd3, also known as RhoE, belongs to the Rnd subclass of the Rho family of small guanosine triphosphate (GTP)-binding proteins. Rnd proteins are unique due to their inability to switch from a GTP-bound to GDP-bound conformation. The basic role of Rnd3 is to report as an endogenous antagonist of RhoA signaling-mediated actin cytoskeleton dynamics, which specifically contributes to cell migration and neuron polarity. Rnd3 also plays a critical role in arresting cell cycle distribution, inhibiting cell growth, and inducing apoptosis and differentiation.
Protocole
Product Specific Protocols | |
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WB protocol for RND3 antibody 66228-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
Publications
Species | Application | Title |
---|---|---|
Mol Ther Nucleic Acids Downregulated lncRNA HOXA11-AS Affects Trophoblast Cell Proliferation and Migration by Regulating RND3 and HOXA7 Expression in PE. | ||
Int J Mol Med Ingenuity pathway analysis of differentially expressed genes involved in signaling pathways and molecular networks in RhoE gene‑edited cardiomyocytes.
| ||
Virology Transcriptomic analysis reveals crucial regulatory roles of immediate-early response genes and related signaling pathways in coronavirus infectious bronchitis virus infection |
Avis
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
FH Yuan (Verified Customer) (12-10-2020) | This antibody is very good quality and can detect RND3 in both U937 and PBMC cells.
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