• Phare
  • Validé par KD/KO

Anticorps Monoclonal anti-RND3

RND3 Monoclonal Antibody for WB,ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain, porc

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

3H8F9

N° de cat : 66228-1-Ig

Synonymes

ARHE, memB, Protein MemB, Rho family GTPase 3, Rho8, RhoE, RND3



Applications testées

Résultats positifs en WBtissu cérébral humain fœtal

Dilution recommandée

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

66228-1-Ig cible RND3 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, porc

Réactivité Humain, porc
Réactivité citéeHumain
Hôte / Isotype Mouse / IgG2b
Clonalité Monoclonal
Type Anticorps
Immunogène RND3 Protéine recombinante Ag18839
Nom complet Rho family GTPase 3
Masse moléculaire calculée 244 aa, 27 kDa
Poids moléculaire observé 29 kDa
Numéro d’acquisition GenBankBC012513
Symbole du gène RND3
Identification du gène (NCBI) 390
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
Conditions de stockageStocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Rnd3, also known as RhoE, belongs to the Rnd subclass of the Rho family of small guanosine triphosphate (GTP)-binding proteins. Rnd proteins are unique due to their inability to switch from a GTP-bound to GDP-bound conformation. The basic role of Rnd3 is to report as an endogenous antagonist of RhoA signaling-mediated actin cytoskeleton dynamics, which specifically contributes to cell migration and neuron polarity. Rnd3 also plays a critical role in arresting cell cycle distribution, inhibiting cell growth, and inducing apoptosis and differentiation.

Protocole

Product Specific Protocols
WB protocol for RND3 antibody 66228-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Mol Ther Nucleic Acids

Downregulated lncRNA HOXA11-AS Affects Trophoblast Cell Proliferation and Migration by Regulating RND3 and HOXA7 Expression in PE.

Authors - Yetao Xu
humanWB

Int J Mol Med

Ingenuity pathway analysis of differentially expressed genes involved in signaling pathways and molecular networks in RhoE gene‑edited cardiomyocytes.

Authors - Zhongming Shao
  • KO Validated
humanWB

Virology

Transcriptomic analysis reveals crucial regulatory roles of immediate-early response genes and related signaling pathways in coronavirus infectious bronchitis virus infection

Authors - Li Xia Yuan

Avis

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


FH

Yuan (Verified Customer) (12-10-2020)

This antibody is very good quality and can detect RND3 in both U937 and PBMC cells.

  • Applications: Western Blot
  • Primary Antibody Dilution: 1:1000
  • Cell Tissue Type: U937 & PBMC