Anticorps Monoclonal anti-PER2
PER2 Monoclonal Antibody for WB, ELISA
Hôte / Isotype
Mouse / IgG1
Réactivité testée
Humain et plus (1)
Applications
WB, IHC, ELISA
Conjugaison
Non conjugué
CloneNo.
2E6C3
N° de cat : 67513-1-Ig
Synonymes
Galerie de données de validation
Applications testées
| Résultats positifs en WB | cellules HEK-293, cellules BxPC-3, cellules HL-60, cellules K-562, cellules L02, cellules THP-1, cellules Y79 |
Dilution recommandée
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Applications publiées
| WB | See 8 publications below |
| IHC | See 1 publications below |
Informations sur le produit
67513-1-Ig cible PER2 dans les applications de WB, IHC, ELISA et montre une réactivité avec des échantillons Humain
| Réactivité | Humain |
| Réactivité citée | Humain, souris |
| Hôte / Isotype | Mouse / IgG1 |
| Clonalité | Monoclonal |
| Type | Anticorps |
| Immunogène | PER2 Protéine recombinante Ag29489 |
| Nom complet | period homolog 2 (Drosophila) |
| Masse moléculaire calculée | 137 kDa |
| Poids moléculaire observé | 150~160 kDa |
| Numéro d’acquisition GenBank | NM_022817 |
| Symbole du gène | PER2 |
| Identification du gène (NCBI) | 8864 |
| Conjugaison | Non conjugué |
| Forme | Liquide |
| Méthode de purification | Purification par protéine A |
| Tampon de stockage | PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3 |
| Conditions de stockage | Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. |
Informations générales
PER2, also named as KIAA0347, is a component of the circadian clock mechanism which is essential for generating circadian rhythms. PER2 is a negative element in the circadian transcriptional loop. PER2 influences clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. It negatively regulates CLOCK|NPAS2-BMAL1|BMAL2-induced transactivation. Defects in PER2 are a cause of familial advanced sleep-phase syndrome (FASPS) which is characterized by very early sleep onset and offset.
Protocole
| Product Specific Protocols | |
|---|---|
| WB protocol for PER2 antibody 67513-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Sci Total Environ Metastatic effects of perfluorooctanoic acid (PFOA) on Drosophila melanogaster with metabolic reprogramming and dysrhythmia in a multigenerational exposure scenario | ||
Cancer Manag Res Circadian Clock Protein PERIOD2 Suppresses the PI3K/Akt Pathway and Promotes Cisplatin Sensitivity in Ovarian Cancer. | ||
J Immunol Res Suppression of DLBCL Progression by the E3 Ligase Trim35 Is Mediated by CLOCK Degradation and NK Cell Infiltration. | ||
Front Mol Biosci Period2 is associated with immune cell infiltration and is a potential diagnostic and prognostic marker for hepatocellular carcinoma | ||
J Cell Sci The actin cytoskeleton-MRTF/SRF cascade transduces cellular physical niche cues to entrain circadian clock | ||
Anesth Analg Sleep Fragmentation, Electroencephalographic Slowing, and Circadian Disarray in a Mouse Model for Intensive Care Unit Delirium |
Avis
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
FH Priya (Verified Customer) (01-05-2023) | I have been using this antibody for human keratinocytes, human cardiomyocytes and mouse tissues like liver and skin
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