Anticorps Monoclonal anti-KLRG1

KLRG1 Monoclonal Antibody for FC

Hôte / Isotype

Golden Syrian Hamster / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

CoraLite®594 Fluorescent Dye

CloneNo.

2F1

N° de cat : CL594-65084

Synonymes

2F1 Ag, Klrg1, MAFA, MAFA L

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Galerie de données de validation

• 

  FC experiment of mouse splenocytes using CL594-65084

  1X10^6 mouse splenocytes were surface stained with 0.5 ug CoraLite®594 Anti-Mouse KLRG1 (CL594-65084, Clone: 2F1), or 0.5 ug Isotype Control. Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: splénocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL594-65084 cible KLRG1 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Golden Syrian Hamster / IgG
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: s/o
• Nom complet: killer cell lectin-like receptor subfamily G, member 1
• Numéro d’acquisition GenBank: BC101953
• Symbole du gène: Klrg1
• Identification du gène (NCBI): 50928
• Conjugaison: CoraLite®594 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 588 nm / 604 nm
• Forme: Liquide
• Méthode de purification: Purification par affinité
• Tampon de stockage: PBS with 0.09% sodium azide.
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

KLRG1 (killer cell lectin-like receptor subfamily G, member 1) is a C-type lectin inhibitory receptor that contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. KLRG1 is expressed by subsets of NK and T cells, existing both as a monomer and as a disulfide-linked homodimer (PMID: 10741410; 19604491). It is considered to be a cell differentiation marker for NK and T cells and is strongly induced by viral and other infections (PMID: 20373518). Through interactions with members of the cadherin family, KLRG1 plays an inhibitory role on NK- and T-cell function (PMID: 19009530; 20373518).