Anticorps Monoclonal anti-KLRG1

KLRG1 Monoclonal Antibody for FC

Hôte / Isotype

Golden Syrian Hamster / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

2F1

N° de cat : CL488-65084

Synonymes

2F1 Ag, Klrg1, MAFA, MAFA L

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Galerie de données de validation

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  FC experiment of mouse splenocytes using CL488-65084

  1X10^6 mouse splenocytes were surface stained with APC Anti-Mouse NK1.1 (CD161) (APC-65138, Clone: PK136) and 5 ul CoraLite® Plus 488 Anti-Mouse KLRG1 (CL488-65084, Clone: 2F1). Cells were not fixed.

• 

  FC experiment of mouse splenocytes using CL488-65084

  1X10^6 mouse splenocytes were surface stained with APC Anti-Mouse NK1.1 (CD161) (APC-65138, Clone: PK136) and CoraLite® Plus 488 conjugated Hamster IgG isotype control. Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: splénocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 μl per 10^6 cells in a 100 µl suspension or 5 μl per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL488-65084 cible KLRG1 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Golden Syrian Hamster / IgG
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: s/o
• Nom complet: killer cell lectin-like receptor subfamily G, member 1
• Numéro d’acquisition GenBank: BC101953
• Symbole du gène: Klrg1
• Identification du gène (NCBI): 50928
• Conjugaison: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 493 nm / 522 nm
• Forme: Liquide
• Méthode de purification: Purification par affinité
• Tampon de stockage: PBS avec azoture de sodium à 0,1 % et BSA à 0,5 %, pH 7,3.
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

KLRG1 (killer cell lectin-like receptor subfamily G, member 1) is a C-type lectin inhibitory receptor that contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. KLRG1 is expressed by subsets of NK and T cells, existing both as a monomer and as a disulfide-linked homodimer (PMID: 10741410; 19604491). It is considered to be a cell differentiation marker for NK and T cells and is strongly induced by viral and other infections (PMID: 20373518). Through interactions with members of the cadherin family, KLRG1 plays an inhibitory role on NK- and T-cell function (PMID: 19009530; 20373518).