Anticorps Monoclonal anti-HOXA7

HOXA7 Monoclonal Antibody for IF

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

IF

Conjugaison

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

2A7H6

N° de cat : CL488-67112

Synonymes

ANTP, homeobox A7, Homeobox protein Hox 1.1, Homeobox protein Hox 1A, Homeobox protein Hox A7, HOX1, HOX1.1, HOX1A, HOXA7

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Galerie de données de validation

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  IF Staining of HepG2 using CL488-67112

  Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using CoraLite® Plus 488 HOXA7 antibody (CL488-67112, Clone: 2A7H6 ) at dilution of 1:200.

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  IF Staining of HepG2 using CL488-67112

  Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using CoraLite® Plus 488 HOXA7 antibody (CL488-67112, Clone: 2A7H6 ) at dilution of 1:200.

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Applications testées

• Résultats positifs en IF: cellules HepG2,

Dilution recommandée

• Immunofluorescence (IF): IF : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

CL488-67112 cible HOXA7 dans les applications de IF et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: HOXA7 Protéine recombinante Ag19025
• Nom complet: homeobox A7
• Masse moléculaire calculée: 230 aa, 25 kDa
• Poids moléculaire observé: 20 kDa
• Numéro d’acquisition GenBank: BC148692
• Symbole du gène: HOXA7
• Identification du gène (NCBI): 3204
• Conjugaison: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 493 nm / 522 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS avec glycérol à 50 %, Proclin300 à 0,05 % et BSA à 0,5 %, pH 7,3.
• Conditions de stockage: Stocker à -20 °C. Éviter toute exposition à la lumière. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

HOX genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene Hoxa-1 is transcriptionally regulated by retinoic acid (RA) and encodes a transcription factor, which has been shown to play important roles in cell differentiation and embryogenesis. Hoxa-1 is also expressed in cancers, such as mammary tumors, though it is not expressed in normal gland or in precancerous mammary tissues. At embryonic stages, Hoxa-2 is expressed in the mesenchyme and epithelial cells of palate, however its expression is restricted to the tips of the growing palatal shelves. Hoxa-2 protein is predominantly expressed in the nuclei of cells in the ventral mantle region of the developing embryo. In the developing and adult mouse spinal cord, Hoxa-2 protein may contribute to dorsal-ventral patterning and/or to the specification of neuronal phenotype. Hoxa-7 functions as a potent transcriptional repressor and its action as such requires several domains, including both activator and repressor regions. Hoxa-7 is expressed in the fetal liver, lung, skeletal muscle, kidney, pancreas and placenta.