Anticorps Monoclonal anti-HOXA7
HOXA7 Monoclonal Antibody for IF, WB,ELISA
Hôte / Isotype
Mouse / IgG1
Réactivité testée
Humain et plus (1)
Applications
WB, IHC, IF, ELISA
Conjugaison
Non conjugué
CloneNo.
2A7H6
N° de cat : 67112-1-Ig
Synonymes
Galerie de données de validation
Applications testées
Résultats positifs en WB | cellules THP-1, cellules HepG2, cellules HL-60, cellules HT-29, cellules K-562, cellules SMMC-7721 |
Résultats positifs en IF | cellules HepG2, |
Dilution recommandée
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:1000-1:6000 |
Immunofluorescence (IF) | IF : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Applications publiées
KD/KO | See 1 publications below |
WB | See 3 publications below |
IHC | See 1 publications below |
IF | See 1 publications below |
Informations sur le produit
67112-1-Ig cible HOXA7 dans les applications de WB, IHC, IF, ELISA et montre une réactivité avec des échantillons Humain
Réactivité | Humain |
Réactivité citée | Humain, souris |
Hôte / Isotype | Mouse / IgG1 |
Clonalité | Monoclonal |
Type | Anticorps |
Immunogène | HOXA7 Protéine recombinante Ag19025 |
Nom complet | homeobox A7 |
Masse moléculaire calculée | 230 aa, 25 kDa |
Poids moléculaire observé | 20 kDa |
Numéro d’acquisition GenBank | BC148692 |
Symbole du gène | HOXA7 |
Identification du gène (NCBI) | 3204 |
Conjugaison | Non conjugué |
Forme | Liquide |
Méthode de purification | Purification par protéine G |
Tampon de stockage | PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3 |
Conditions de stockage | Stocker à -20 ℃. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. |
Informations générales
HOX genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene Hoxa-1 is transcriptionally regulated by retinoic acid (RA) and encodes a transcription factor, which has been shown to play important roles in cell differentiation and embryogenesis. Hoxa-1 is also expressed in cancers, such as mammary tumors, though it is not expressed in normal gland or in precancerous mammary tissues. At embryonic stages, Hoxa-2 is expressed in the mesenchyme and epithelial cells of palate, however its expression is restricted to the tips of the growing palatal shelves. Hoxa-2 protein is predominantly expressed in the nuclei of cells in the ventral mantle region of the developing embryo. In the developing and adult mouse spinal cord, Hoxa-2 protein may contribute to dorsal-ventral patterning and/or to the specification of neuronal phenotype. Hoxa-7 functions as a potent transcriptional repressor and its action as such requires several domains, including both activator and repressor regions. Hoxa-7 is expressed in the fetal liver, lung, skeletal muscle, kidney, pancreas and placenta.
Protocole
Product Specific Protocols | |
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WB protocol for HOXA7 antibody 67112-1-Ig | Download protocol |
IF protocol for HOXA7 antibody 67112-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
Publications
Species | Application | Title |
---|---|---|
Reprod Sci CircPAPPA Regulates the Proliferation, Migration, Invasion, Apoptosis, and Cell Cycle of Trophoblast Cells Through the miR-3127-5p/HOXA7 Axis. | ||
J Orthop Surg Res MiR-920 promotes osteogenic differentiation of human bone mesenchymal stem cells by targeting HOXA7. | ||
Cancer Sci Homeobox A7 promotes esophageal squamous cell carcinoma progression through C-C motif chemokine ligand 2-mediated tumor-associated macrophage recruitment
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