Anticorps Monoclonal anti-HOXA7

HOXA7 Monoclonal Antibody for IF, WB,ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain et plus (1)

Applications

WB, IHC, IF, ELISA

Conjugaison

Non conjugué

CloneNo.

2A7H6

N° de cat : 67112-1-Ig

Synonymes

ANTP, homeobox A7, Homeobox protein Hox 1.1, Homeobox protein Hox 1A, Homeobox protein Hox A7, HOX1, HOX1.1, HOX1A, HOXA7



Applications testées

Résultats positifs en WBcellules THP-1, cellules HepG2, cellules HL-60, cellules HT-29, cellules K-562, cellules SMMC-7721
Résultats positifs en IFcellules HepG2,

Dilution recommandée

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

67112-1-Ig cible HOXA7 dans les applications de WB, IHC, IF, ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Réactivité citéeHumain, souris
Hôte / Isotype Mouse / IgG1
Clonalité Monoclonal
Type Anticorps
Immunogène HOXA7 Protéine recombinante Ag19025
Nom complet homeobox A7
Masse moléculaire calculée 230 aa, 25 kDa
Poids moléculaire observé 20 kDa
Numéro d’acquisition GenBankBC148692
Symbole du gène HOXA7
Identification du gène (NCBI) 3204
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine G
Tampon de stockage PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
Conditions de stockageStocker à -20 ℃. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

HOX genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene Hoxa-1 is transcriptionally regulated by retinoic acid (RA) and encodes a transcription factor, which has been shown to play important roles in cell differentiation and embryogenesis. Hoxa-1 is also expressed in cancers, such as mammary tumors, though it is not expressed in normal gland or in precancerous mammary tissues. At embryonic stages, Hoxa-2 is expressed in the mesenchyme and epithelial cells of palate, however its expression is restricted to the tips of the growing palatal shelves. Hoxa-2 protein is predominantly expressed in the nuclei of cells in the ventral mantle region of the developing embryo. In the developing and adult mouse spinal cord, Hoxa-2 protein may contribute to dorsal-ventral patterning and/or to the specification of neuronal phenotype. Hoxa-7 functions as a potent transcriptional repressor and its action as such requires several domains, including both activator and repressor regions. Hoxa-7 is expressed in the fetal liver, lung, skeletal muscle, kidney, pancreas and placenta.

Protocole

Product Specific Protocols
WB protocol for HOXA7 antibody 67112-1-IgDownload protocol
IF protocol for HOXA7 antibody 67112-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Reprod Sci

CircPAPPA Regulates the Proliferation, Migration, Invasion, Apoptosis, and Cell Cycle of Trophoblast Cells Through the miR-3127-5p/HOXA7 Axis.

Authors - Jun Li
humanWB

J Orthop Surg Res

MiR-920 promotes osteogenic differentiation of human bone mesenchymal stem cells by targeting HOXA7.

Authors - Jun-Pu Zha
human,mouseWB,IHC,IF

Cancer Sci

Homeobox A7 promotes esophageal squamous cell carcinoma progression through C-C motif chemokine ligand 2-mediated tumor-associated macrophage recruitment

Authors - Anqi Feng
  • KD Validated