Anticorps Polyclonal de lapin anti-Fabp4

Fabp4 Polyclonal Antibody for ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris et plus (1)

Applications

WB, IF,ELISA

Conjugaison

Non conjugué

Publications

2

N° de cat : 51035-1-AP

Synonymes

422/aP2, ALBP/Ap2, Ap2, Fabp4, Lbpl

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Galerie de données de validation

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  WB analysis of mouse skin using 51035-1-AP

  mouse skin tissue were subjected to SDS PAGE followed by western blot with 51035-1-AP (Fabp4 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse small intestine using 51035-1-AP

  mouse small intestine tissue were subjected to SDS PAGE followed by western blot with 51035-1-AP (Fabp4 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse heart using 51035-1-AP

  mouse heart tissue were subjected to SDS PAGE followed by western blot with 51035-1-AP (Fabp4 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Applications testées

Dilution recommandée

Application	Dilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 1 publications below
• IF: See 1 publications below

Informations sur le produit

51035-1-AP cible Fabp4 dans les applications de WB, IF,ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Réactivité citée: porc, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Fabp4 Protéine recombinante Ag0712
• Nom complet: fatty acid binding protein 4, adipocyte
• Masse moléculaire calculée: 15 kDa
• Poids moléculaire observé: 15 kDa
• Numéro d’acquisition GenBank: BC054426
• Symbole du gène: Fabp4
• Identification du gène (NCBI): 11770
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20 ℃. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Fatty acid binding protein (FABP) 4 is a member of the FABP family which abundantly expressed, fatty acid carrier proteins. FABPs are capable of binding a variety of hydrophobic molecules such as long-chain fatty acids and are important for their uptake and intracellular trafficking. It was first identified as an adipocyte-specific protein, important for the maintenance of lipid and glucose metabolism. It is also detected in macrophages, where it participates in regulating inflammation and cholesterol trafficking via NFκB and PPAR. In more recent studies, FABP4 has been found in a variety of endothelial cells, where it has been identified as a target of VEGF and a regulator of cell proliferation and possibly angiogenesis. Pathologically, FABP4 has been associated with the development of metabolic syndrome, diabetes and cancer and vulnerability of atherosclerotic plaques. FABP4 has been identified as a novel prognostic factor for both adverse cardiovascular events and breast cancer.

Publications

Species	Application	Title
mouse	IF	Cell; Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis.; Authors - Daniel Kopinke
pig	WB	J Anim Sci; Antimicrobial peptide KR-32 alleviates Escherichia coli K88-induced fatty acid malabsorption by improving expression of FATP4.; Authors - H Liu