Anticorps Monoclonal anti-FGF18

FGF18 Monoclonal Antibody for WB,ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain, Lapin, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

Publications

1

CloneNo.

1D11D12

N° de cat : 60341-1-Ig

Synonymes

FGF 18, FGF18, fibroblast growth factor 18, ZFGF5

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Galerie de données de validation

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  WB analysis of HT-1080 using 60341-1-Ig

  HT-1080 cells were subjected to SDS PAGE followed by western blot with 60341-1-Ig (FGF18 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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  WB analysis of NIH/3T3 using 60341-1-Ig

  NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 60341-1-Ig (FGF18 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules HT-1080, cellules NIH/3T3

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 1 publications below

Informations sur le produit

60341-1-Ig cible FGF18 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, Lapin, souris

• Réactivité: Humain, Lapin, souris
• Réactivité citée: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: FGF18 Protéine recombinante Ag2041
• Nom complet: fibroblast growth factor 18
• Masse moléculaire calculée: 207 aa, 24 kDa
• Poids moléculaire observé: 21 kDa
• Numéro d’acquisition GenBank: BC006245
• Symbole du gène: FGF18
• Identification du gène (NCBI): 8817
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.

Publications

Species	Application	Title
human	WB	J Exp Clin Cancer Res; HDAC7 promotes NSCLC proliferation and metastasis via stabilization by deubiquitinase USP10 and activation of β-catenin-FGF18 pathway.; Authors - Kai Guo