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Anticorps Monoclonal anti-EMILIN1

EMILIN1 Monoclonal Antibody for IF

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

IF

Conjugaison

CoraLite®594 Fluorescent Dye

CloneNo.

2A5C8

N° de cat : CL594-60047

Synonymes

DKFZp586M121, EMI, EMILIN, EMILIN 1, EMILIN1, gp115

Galerie de données de validation

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  • Immunofluorescence (IF) / fluorescent staining of human ovary tumor tissue using CoraLite®594-conjugated EMILIN1 Monoclonal antibod (CL594-60047)

    IF Staining of human ovary tumor using CL594-60047

    Immunofluorescent analysis of (4% PFA) fixed human ovary tumor tissue using CoraLite®594 EMILIN1 antibody (CL594-60047, Clone: 2A5C8 ) at dilution of 1:200.

  • Immunofluorescence (IF) / fluorescent staining of human ovary tumor tissue using CoraLite®594-conjugated EMILIN1 Monoclonal antibod (CL594-60047)

    IF Staining of human ovary tumor using CL594-60047

    Immunofluorescent analysis of (4% PFA) fixed human ovary tumor tissue using CoraLite®594 EMILIN1 antibody (CL594-60047, Clone: 2A5C8 ) at dilution of 1:200.

Applications testées

Résultats positifs en IFtissu de tumeur ovarienne humain,

Dilution recommandée

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL594-60047 cible EMILIN1 dans les applications de IF et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Mouse / IgG1
Clonalité Monoclonal
Type Anticorps
Immunogène EMILIN1 Protéine recombinante Ag1016
Nom complet elastin microfibril interfacer 1
Masse moléculaire calculée 107 kDa
Poids moléculaire observé 120-130 kDa
Numéro d’acquisition GenBankBC007530
Symbole du gène EMILIN1
Identification du gène (NCBI) 11117
Conjugaison CoraLite®594 Fluorescent Dye
Excitation/Emission maxima wavelengths588 nm / 604 nm
Forme Liquide
Méthode de purification Purification par protéine G
Tampon de stockage PBS avec glycérol à 50 %, Proclin300 à 0,05 % et BSA à 0,5 %, pH 7,3.
Conditions de stockageStocker à -20 °C. Éviter toute exposition à la lumière. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

EMILIN1, also named as EMILIN, EMILIN-1, gp115 and EMI, may be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. It has cell adhesive capacity. EMILIN1 is a negative regulator of the transforming growth factor-beta (TGF-beta) signaling, which is involved in blood pressure (BP) homeostasis (PMID:20186130). EMILIN1 may play a key role in hypertensive vascular remodeling. TGFβ proteins are the main regulators of blood vessel development and maintenance, and EMILIN1 inhibits TGFβ signaling by binding specifically to the proTGFβ precursor and preventing its maturation by furin convertases in the extracellular space (PMID:19922630).

Protocole

Product Specific Protocols
IF protocol for CL594 EMILIN1 antibody CL594-60047Download protocol
Standard Protocols
Click here to view our Standard Protocols