Anticorps Monoclonal anti-CD90.2

CD90.2 Monoclonal Antibody for FC

Hôte / Isotype

Rat / IgG2b, kappa

Réactivité testée

souris

Applications

FC

Conjugaison

FITC Plus Fluorescent Dye

Publications

2

CloneNo.

30-H12

N° de cat : FITC-65088

Synonymes

CD90, T25, Thy 1, Thy 1.2, Thy1, Thy1.1, Thy1.2, thymus cell antigen 1, theta

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Galerie de données de validation

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  FC experiment of mouse splenocytes using FITC-65088

  1X10^6 mouse splenocytes were surface co-stained with Anti-Mouse CD3ε and 0.25 ug FITC Anti-Mouse CD90.2 (FITC-65088, Clone:30-H12) or 0.25 ug Control Antibody. Cells were not fixed.

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  FC experiment of mouse thymocytes using FITC-65088

  1X10^6 mouse thymocytes were surface stained with 0.5 ug FITC Anti-Mouse CD90.2 (FITC-65088, Clone:30-H12) (red) or 0.5 ug Control Antibody. Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: splénocytes de souris, thymocytes de souris

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Applications publiées

• FC: See 2 publications below

Informations sur le produit

FITC-65088 cible CD90.2 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Réactivité citée: souris
• Hôte / Isotype: Rat / IgG2b, kappa
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Thymus ou rate de souris
• Nom complet: thymus cell antigen 1, theta
• Numéro d’acquisition GenBank: BC054436
• Symbole du gène: Thy1
• Identification du gène (NCBI): 21838
• Conjugaison: FITC Plus Fluorescent Dye
• Excitation/Emission maxima wavelengths: 495 nm / 524 nm
• Forme: Liquide
• Méthode de purification: Purification par affinité
• Tampon de stockage: PBS with 0.09% sodium azide.
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD90 (Thy-1) is a 25 kDa, GPI-linked membrane glycoprotein that belongs to immunoglobulin superfamily (PMID: 6177036; 6153212). Originally described as a brain thymus cross-reactive antigen, it is found in large quantities on mouse and rat thymocytes and central nervous system cells (PMID: 83175). CD90 has been postulated to be involved in cellular recognition, adherence, and T cell activation (PMID: 7683034). Mouse CD90 (Thy-1) is defined as a differentiation alloantigen, represented as two serologically distinguishable allelic forms, designated CD90.1 (Thy-1.1) and CD90.2 (Thy-1.2) (PMID: 83175). CD90.2 is expressed by thymocytes, T cells, neurons and hematopoietic stem cells in most strains of mice (C3H, BALB/c, C57BL/6, DBA, and others), whereas CD90.1 is expressed in some mouse strains like AKR (PMID: 5919593).

Publications

Species	Application	Title
mouse	FC	Stem Cell Res Ther; Endoplasmic reticulum stress modulates the fate of lung resident mesenchymal stem cell to myofibroblast via C/EBP homologous protein during pulmonary fibrosis.; Authors - Xiaoyu Yang
	FC	Exp Ther Med; Adipose-derived mesenchymal stem cell exosomes inhibit transforming growth factor-β1-induced collagen synthesis in oral mucosal fibroblasts.; Authors - Junjie Liu