Anticorps Monoclonal anti-CD80 (B7-1)
CD80 (B7-1) Monoclonal Antibody for FC
Hôte / Isotype
Armenian Hamster / IgG
Réactivité testée
souris
Applications
FC
Conjugaison
CoraLite® Plus 750 Fluorescent Dye
CloneNo.
16-10A1
N° de cat : CL750-65076
Synonymes
Galerie de données de validation
Applications testées
Résultats positifs en cytométrie | macrophages péritonéaux de souris |
Dilution recommandée
Application | Dilution |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Informations sur le produit
CL750-65076 cible CD80 (B7-1) dans les applications de FC et montre une réactivité avec des échantillons souris
Réactivité | souris |
Hôte / Isotype | Armenian Hamster / IgG |
Clonalité | Monoclonal |
Type | Anticorps |
Immunogène | Lignée de cellules CHO transfectées avec B7 (CD80) de souris |
Nom complet | CD80 antigen |
Numéro d’acquisition GenBank | BC131959 |
Symbole du gène | Cd80 |
Identification du gène (NCBI) | 12519 |
Conjugaison | CoraLite® Plus 750 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 755 nm / 780 nm |
Forme | Liquide |
Méthode de purification | Unknow |
Tampon de stockage | PBS with 0.09% sodium azide. |
Conditions de stockage | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Informations générales
CD80 (also known as B7-1) is a type I membrane protein that is a member of the immunoglobulin superfamily, with an extracellular immunoglobulin constant-like domain and a variable-like domain required for receptor binding. It is expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, monocytes, and macrophages. CD80 is the receptor for the proteins CD28 and CTLA-4 found on the surface of T-cells. It is involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. CD80 also acts as a cellular attachment receptor for adenovirus subgroup B. (PMID: 7545666; 12015893; 16920215)
Protocole
Product Specific Protocols | |
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FC protocol for CL Plus 750 CD80 (B7-1) antibody CL750-65076 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |