Anticorps Monoclonal anti-CD62P

CD62P Monoclonal Antibody for FC

Hôte / Isotype

Mouse / IgG1, kappa

Réactivité testée

Humain, primates non humains

Applications

FC

Conjugaison

Non conjugué

CloneNo.

AK4

N° de cat : 65164-1-Ig

Synonymes

AK4, CD62, CD62P, FLJ45155, GMP 140, GMP140, GMRP, Granule membrane protein 140, GRMP, LECAM3, P selectin, PADGEM, PSEL, SELP

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Galerie de données de validation

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  FC experiment of human peripheral blood platelets using 65164-1-Ig

  1X10^6 thrombin-activated human peripheral blood platelets were surface co-stained with Anti-Human CD41a labeled with FlexAble CL488 and 0.2 ug Anti-Human CD62P (65164-1-Ig, Clone:AK4) labeled with FlexAble CL647. Cells were not fixed.

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  FC experiment of human peripheral blood platelets using 65164-1-Ig

  1X10^6 thrombin-activated human peripheral blood platelets were surface stained with 0.2 ug Anti-Human CD62P (65164-1-Ig, Clone:AK4) labeled with FlexAble CL647. Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: plaquettes de sang périphérique humain,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

65164-1-Ig cible CD62P dans les applications de FC et montre une réactivité avec des échantillons Humain, primates non humains

• Réactivité: Humain, primates non humains
• Hôte / Isotype: Mouse / IgG1, kappa
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Plaquettes humaines
• Nom complet: selectin P (granule membrane protein 140kDa, antigen CD62)
• Masse moléculaire calculée: 830 aa, 91 kDa
• Numéro d’acquisition GenBank: BC028067
• Symbole du gène: SELP
• Identification du gène (NCBI): 6403
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purifié par chromatographie d'affinité par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide.
• Conditions de stockage: Store at 2-8°C. Stable for one year after shipment.

Informations générales

P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.