Anticorps Monoclonal anti-CD62L

CD62L Monoclonal Antibody for FC

Hôte / Isotype

Mouse / Mouse IgG1

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

DREG56

N° de cat : 65167-1-Ig

Synonymes

CD62L, gp90 MEL, hLHRc, L selectin, LAM 1, LAM1, LECAM1, Leu 8, Leukocyte adhesion molecule 1, LNHR, LSEL, Lyam 1, LYAM1, Lymph node homing receptor, PLNHR, selectin L, SELL, TQ1

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Galerie de données de validation

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  FC experiment of human peripheral blood lymphocytes using 65167-1-Ig

  1X10^6 human peripheral blood lymphocytes were surface stained with 0.5 ug Anti-Human CD62L (65167-1-Ig, Clone: DREG56) (green) or 0.5 ug isotype control antibody (black), and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: lymphocytes de sang périphérique humain,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

65167-1-Ig cible CD62L dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / Mouse IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Leucocytes de sang périphérique humain activés par PMA
• Nom complet: selectin L
• Masse moléculaire calculée: 42 kDa
• Numéro d’acquisition GenBank: BC020758
• Symbole du gène: SELL
• Identification du gène (NCBI): 6402
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purifié par chromatographie d'affinité par protéine A
• Tampon de stockage: PBS avec azoture de sodium à 0,1 %.
• Conditions de stockage: Stocker à une température comprise entre 2 °C et 8 °C.

Informations générales

CD62L, also known as L-selectin or SELL, is a member of the selectin family of adhesion molecules that also include CD62E (E-selectin) and CD62P (P-selectin) (PMID: 2663882, 2473156, 1382078). CD62L is a highly glycosylated protein of 95-105 kDa on neutrophils and 74 kDa on lymphocytes (PMID: 1382078; 1694883, 1695155). CD62L is expressed on the surface of most leukocytes, including lymphocytes, neutrophils, monocytes, eosinophils, hematopoietic progenitor cells, and immature thymocytes (PMID: 1694883, 1688580). It mediates the binding of lymphocytes to high endothelial venules (HEV) of peripheral lymph nodes through interactions with a constitutively expressed ligand, and is also involved in lymphocyte, neutrophil, and monocyte attachment to endothelium at sites of inflammation (PMID: 1382078).