Anticorps Monoclonal anti-CD45R (B220)
CD45R (B220) Monoclonal Antibody for FC
Hôte / Isotype
Rat / IgG2a, kappa
Réactivité testée
Humain, souris
Applications
FC
Conjugaison
CoraLite®594 Fluorescent Dye
CloneNo.
RA3-6B2
N° de cat : CL594-65139
Synonymes
Galerie de données de validation
Applications testées
Résultats positifs en cytométrie | splénocytes de souris, |
Dilution recommandée
Application | Dilution |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Informations sur le produit
CL594-65139 cible CD45R (B220) dans les applications de FC et montre une réactivité avec des échantillons Humain, souris
Réactivité | Humain, souris |
Hôte / Isotype | Rat / IgG2a, kappa |
Clonalité | Monoclonal |
Type | Anticorps |
Immunogène | Cellules tumorales pré-B induites par le virus de la leucémie murine d'Abelson |
Nom complet | protein tyrosine phosphatase, receptor type, C |
Numéro d’acquisition GenBank | BC028512 |
Symbole du gène | Ptprc |
Identification du gène (NCBI) | 19264 |
Conjugaison | CoraLite®594 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 588 nm / 604 nm |
Forme | Liquide |
Méthode de purification | Purification par affinité |
Tampon de stockage | PBS with 0.09% sodium azide. |
Conditions de stockage | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Informations générales
CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097). CD45R (B220) is an isoform of CD45, expressed on murine B-lineage cells (except for plasma cells) and on a small sub-population of T cells (PMID: 6975314; 15712182). It is commonly used as a pan B-cell marker in mice. CD45R is also expressed on activated T cells and NK cell subsets (PMID: 7514808; 17923504). The RA3-6B2 clone reacts with human and mouse CD45R.
Protocole
Product Specific Protocols | |
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FC protocol for CL594 CD45R (B220) antibody CL594-65139 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |