Anticorps Monoclonal anti-CD45R (B220)

CD45R (B220) Monoclonal Antibody for FC

Hôte / Isotype

Rat / IgG2a, kappa

Réactivité testée

Humain, souris

Applications

FC

Conjugaison

CoraLite® Plus 405 Fluorescent Dye

CloneNo.

RA3-6B2

N° de cat : CL405-65139

Synonymes

B220, Cd45, CD45R, loc, Ly 5, Lyt 4, Ptprc, T200



Applications testées

Résultats positifs en cytométriesplénocytes de souris,

Dilution recommandée

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL405-65139 cible CD45R (B220) dans les applications de FC et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Hôte / Isotype Rat / IgG2a, kappa
Clonalité Monoclonal
Type Anticorps
Immunogène Cellules tumorales pré-B induites par le virus de la leucémie murine d'Abelson
Nom complet protein tyrosine phosphatase, receptor type, C
Numéro d’acquisition GenBankBC028512
Symbole du gène Ptprc
Identification du gène (NCBI) 19264
Conjugaison CoraLite® Plus 405 Fluorescent Dye
Excitation/Emission maxima wavelengths399 nm / 422 nm
Forme Liquide
Méthode de purification Purification par affinité
Tampon de stockage PBS with 0.09% sodium azide.
Conditions de stockageStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097). CD45R (B220) is an isoform of CD45, expressed on murine B-lineage cells (except for plasma cells) and on a small sub-population of T cells (PMID: 6975314; 15712182). It is commonly used as a pan B-cell marker in mice. CD45R is also expressed on activated T cells and NK cell subsets (PMID: 7514808; 17923504). The RA3-6B2 clone reacts with human and mouse CD45R.

Protocole

Product Specific Protocols
FC protocol for CL Plus 405 CD45R (B220) antibody CL405-65139Download protocol
Standard Protocols
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