Anticorps Monoclonal anti-CD45

CD45 Monoclonal Antibody for FC

Hôte / Isotype

Mouse / IgG1, kappa

Réactivité testée

rat

Applications

FC

Conjugaison

PE Fluorescent Dye

CloneNo.

OX1

N° de cat : PE-65228

Synonymes

CD45, L CA, Lca, Ptprc, RT7, T200

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Galerie de données de validation

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  FC experiment of rat splenocytes using PE-65228

  1X10^6 rat splenocytes were surface stained with 0.2 ug PE Anti-Rat CD45 (PE-65228, Clone:OX1) (red), or 0.2 ug PE Mouse IgG1 Isotype Control (MOPC-21) (PE-65124, Clone: MOPC-21) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: splénocytes de rat

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

PE-65228 cible CD45 dans les applications de FC et montre une réactivité avec des échantillons rat

• Réactivité: rat
• Hôte / Isotype: Mouse / IgG1, kappa
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: s/o
• Nom complet: protein tyrosine phosphatase, receptor type, C
• Masse moléculaire calculée: 143 kDa
• Numéro d’acquisition GenBank: XM_006249910
• Symbole du gène: Ptprc
• Identification du gène (NCBI): 24699
• Conjugaison: PE Fluorescent Dye
• Excitation/Emission maxima wavelengths: 496 nm, 565 nm / 578 nm
• Forme: Liquide
• Méthode de purification: Purification par affinité
• Tampon de stockage: PBS with 0.1% sodium azide and 0.5% BSA.
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097).