Anticorps Monoclonal anti-CD38

CD38 Monoclonal Antibody for FC

Hôte / Isotype

Rat / IgG2a, kappa

Réactivité testée

souris

Applications

FC

Conjugaison

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

90

N° de cat : CL488-65059

Synonymes

Cd38, CD38 antigen, Cd38 rs1

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Galerie de données de validation

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  FC experiment of mouse splenocytes using CL488-65059

  1X10^6 C57BL/6 mouse splenocytes were surface stained with APC Anti-Mouse CD3ε (APC-65060, Clone: 145-2C11) and 1 ug CoraLite® Plus 488-conjugated Anti-Mouse CD38 (CL488-65059, Clone: 90). Cells were not fixed.

• 

  FC experiment of mouse splenocytes using CL488-65059

  1X10^6 C57BL/6 mouse splenocytes were surface stained with APC Anti-Mouse CD3ε (APC-65060, Clone: 145-2C11) and CoraLite® Plus 488-conjugated Rat IgG2a isotype control antibody. Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: splénocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL488-65059 cible CD38 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Rat / IgG2a, kappa
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Cellules pré-B médullaires de souris
• Nom complet: CD38 antigen
• Numéro d’acquisition GenBank: BC046312
• Symbole du gène: Cd38
• Identification du gène (NCBI): 12494
• Conjugaison: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 493 nm / 522 nm
• Forme: Liquide
• Méthode de purification: Purification par affinité
• Tampon de stockage: PBS avec azoture de sodium à 0,1 % et BSA à 0,5 %, pH 7,3.
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).