Anticorps Monoclonal anti-CD36

CD36 Monoclonal Antibody for FC

Hôte / Isotype

Mouse / IgM, kappa

Réactivité testée

Humain

Applications

FC

Conjugaison

CoraLite® Plus 750 Fluorescent Dye

CloneNo.

SMΦ

N° de cat : CL750-65248

Synonymes

CD36, CHDS7, FAT, Fatty acid translocase, Glycoprotein IIIb, GP3B, GP4, GPIIIB, GPIV, PAS 4, PAS IV, PASIV, Platelet collagen receptor, Platelet glycoprotein 4, Platelet glycoprotein IV, SCARB3, Thrombospondin receptor

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Galerie de données de validation

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  FC experiment of human peripheral blood platelets using CL750-65248

  1X10^6 human peripheral blood platelets were surface stained with 5 ul CoraLite® Plus 750 Anti-Human CD36 (CL750-65248, Clone:SMΦ), or CoraLite® Plus 750 Mouse IgM Isotype Control. Cells were not fixed. CD41a positive cells were gated.

• 

  FC experiment of human peripheral blood platelets using CL750-65248

  1X10^6 human peripheral blood platelets were surface stained with 5 ul CoraLite® Plus 750 Anti-Human CD36 (CL750-65248, Clone:SMΦ), or CoraLite® Plus 750 Mouse IgM Isotype Control. Cells were not fixed. CD41a positive cells were gated.

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Applications testées

• Résultats positifs en cytométrie: plaquettes de sang périphérique humain,

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL750-65248 cible CD36 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgM, kappa
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: s/o
• Nom complet: CD36 molecule (thrombospondin receptor)
• Masse moléculaire calculée: 472 aa, 53 kDa
• Numéro d’acquisition GenBank: BC008406
• Symbole du gène: CD36
• Identification du gène (NCBI): 948
• Conjugaison: CoraLite® Plus 750 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 755 nm / 780 nm
• Forme: Liquide
• Méthode de purification: Purification par affinité
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA.
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD36, also named as GP3B and GP4, is an 88-kDa membrane glycoprotein present on platelets, monocytes, erythroid precursors, endothelial cells, and several tumor cell lines. CD36 binds to collagen, thrombospondin, anionic phospholipids, long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport and oxidized LDL. CD36 may function as a cell adhesion molecule. It mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Mutation of CD36 will cause platelet glycoprotein IV deficiency which known as CD36 deficiency. Genetic variations in CD36 are associated with susceptibility to coronary heart disease type 7 (CHDS7).