• Aperçu
  • Applications testées
  • Informations sur le produit
  • Publications (4)
  • Protocole

Anticorps Monoclonal anti-CD31

CD31 Monoclonal Antibody for FC, IF

Hôte / Isotype

Rat / IgG2a, kappa

Réactivité testée

souris et plus (1)

Applications

IF, FC

Conjugaison

FITC Plus Fluorescent Dye

CloneNo.

390

N° de cat : FITC-65058

Synonymes

C85791, Cd31, Pecam, PECAM 1, Pecam1



Applications testées

Résultats positifs en IFcellules bEnd.3,
Résultats positifs en cytométriecellules médullaires de souris

Dilution recommandée

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

FITC-65058 cible CD31 dans les applications de IF, FC et montre une réactivité avec des échantillons souris

Réactivité souris
Réactivité citéerat, souris
Hôte / Isotype Rat / IgG2a, kappa
Clonalité Monoclonal
Type Anticorps
Immunogène Lignée de cellules progénitrices hématopoïétiques 32D de souris C3H/HeJ
Nom complet platelet/endothelial cell adhesion molecule 1
Numéro d’acquisition GenBankBC008519
Symbole du gène Pecam1
Identification du gène (NCBI) 18613
Conjugaison FITC Plus Fluorescent Dye
Excitation/Emission maxima wavelengths495 nm / 524 nm
Forme Liquide
Méthode de purification Purification par affinité
Tampon de stockage PBS with 0.09% sodium azide.
Conditions de stockageStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489).

Protocole

Product Specific Protocols
IF protocol for FITC Plus CD31 antibody FITC-65058Download protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

  • Journal Impact Factor
  • Most recent
SpeciesApplicationTitle
mouseIF

Cell Death Dis

LncRNA ANRIL mediates endothelial dysfunction through BDNF downregulation in chronic kidney disease.

Authors - Hong Su
mouseFC

Bone

mTORC1 coordinates NF-κB signaling pathway to promote chondrogenic differentiation of tendon cells in heterotopic ossification

Authors - Jiaming Fu
ratFC

Cells

Enhancement of Tendon Repair Using Tendon-Derived Stem Cells in Small Intestinal Submucosa via M2 Macrophage Polarization

Authors - Xufeng Mao
mouseFC

Biochim Biophys Acta Mol Cell Res

CARM1 deficiency inhibits osteoblastic differentiation of bone marrow mesenchymal stem cells and delays osteogenesis in mice

Authors - Jing-Yi Li

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