Anticorps Monoclonal anti-CD19
CD19 Monoclonal Antibody for FC
Hôte / Isotype
Rat / IgG2a
Réactivité testée
souris
Applications
FC
Conjugaison
Non conjugué
CloneNo.
1D3
N° de cat : 65290-1-Ig
Synonymes
Galerie de données de validation
Applications testées
Résultats positifs en cytométrie | splénocytes de souris |
Dilution recommandée
Application | Dilution |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Informations sur le produit
65290-1-Ig cible CD19 dans les applications de FC et montre une réactivité avec des échantillons souris
Réactivité | souris |
Hôte / Isotype | Rat / IgG2a |
Clonalité | Monoclonal |
Type | Anticorps |
Immunogène | Mouse CD19 Transfected Cell Line |
Nom complet | CD19 antigen |
Numéro d’acquisition GenBank | BC156767 |
Symbole du gène | Cd19 |
Identification du gène (NCBI) | 12478 |
Conjugaison | Non conjugué |
Forme | Liquide |
Méthode de purification | Purification par affinité |
Tampon de stockage | PBS with 0.09% sodium azide. |
Conditions de stockage | Store at 2-8°C. Stable for one year after shipment. |
Informations générales
CD19 is a 95 kDa type I transmembrane glycoprotein belonging to the immunoglobulin superfamily (PMID: 2472450). It is expressed by B cells and follicular dendritic cells. CD19 is up-regulated at the step of B-lineage commitment during the differentiation of the hematopoietic stem cell, it remains on during subsequent stages of differentiation until finally down-regulated during terminal differentiation into plasma cells (PMID: 8528044). CD19 is involved in B cell development, activation and differentiation. It is the dominant component for the signaling complex on B cells that includes CD21 (CR2), CD81 (TAPA-1) and CD225 and acts as a critical co-receptor for BCR signal transduction (PMID: 23210908).
Protocole
Product Specific Protocols | |
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FC protocol for CD19 antibody 65290-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |