Anticorps Monoclonal anti-CD11b

CD11b Monoclonal Antibody for FC

Hôte / Isotype

Mouse / IgG2a, kappa

Réactivité testée

rat

Applications

FC

Conjugaison

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

OX42

N° de cat : CL488-65229

Synonymes

Cd11b, integrin alpha M, Itgam



Applications testées

Résultats positifs en cytométriesplénocytes de rat

Dilution recommandée

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL488-65229 cible CD11b dans les applications de FC et montre une réactivité avec des échantillons rat

Réactivité rat
Hôte / Isotype Mouse / IgG2a, kappa
Clonalité Monoclonal
Type Anticorps
Immunogène Rat peritoneal macrophages
Nom complet integrin alpha M
Masse moléculaire calculée127 kDa
Numéro d’acquisition GenBankNM_012711
Symbole du gène Itgam
Identification du gène (NCBI) 25021
Conjugaison CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Forme Liquide
Méthode de purification Purification par affinité
Tampon de stockage PBS with 0.09% sodium azide.
Conditions de stockageStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).

Protocole

Product Specific Protocols
FC protocol for CL Plus 488 CD11b antibody CL488-65229Download protocol
Standard Protocols
Click here to view our Standard Protocols