• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

Anticorps Monoclonal anti-CD11a

CD11a Monoclonal Antibody for FC

Hôte / Isotype

Mouse / IgG1, kappa

Réactivité testée

Humain

Applications

FC

Conjugaison

FITC Plus Fluorescent Dye

CloneNo.

TS2/4

N° de cat : FITC-65194

Synonymes

CD11A, Integrin alpha L, ITGAL, LFA 1, LFA 1A, LFA1A

Galerie de données de validation

Filter:
  • Flow cytometry (FC) experiment of human PBMCs using FITC Plus Anti-Human CD11a (TS2/4) (FITC-65194)

    FC experiment of human PBMCs using FITC-65194

    1X10^6 human PBMCs were surface stained with 5 ul FITC Plus Anti-Human CD11a (FITC-65194, Clone: TS2/4), or Mouse IgG1 Isotype Control. Lymphocytes were gated.

  • Flow cytometry (FC) experiment of human PBMCs using FITC Plus Anti-Human CD11a (TS2/4) (FITC-65194)

    FC experiment of human PBMCs using FITC-65194

    1X10^6 human PBMCs were surface stained with 5 ul FITC Plus Anti-Human CD11a (FITC-65194, Clone: TS2/4), or Mouse IgG1 Isotype Control. Lymphocytes were gated.

Applications testées

Résultats positifs en cytométrieCMSP humaines,

Dilution recommandée

ApplicationDilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 μl per 10^6 cells in a 100 µl suspension or 5 μl per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

FITC-65194 cible CD11a dans les applications de FC et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Mouse / IgG1, kappa
Clonalité Monoclonal
Type Anticorps
Immunogène Lignée de CTL HLA-DR
Nom complet integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
Masse moléculaire calculée 129 kDa
Numéro d’acquisition GenBankBC008777
Symbole du gène ITGAL
Identification du gène (NCBI) 3683
Conjugaison FITC Plus Fluorescent Dye
Excitation/Emission maxima wavelengths495 nm / 524 nm
Forme Liquide
Méthode de purification Purification par protéine G
Tampon de stockage PBS with 0.09% sodium azide and 0.5% BSA.
Conditions de stockageStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160).