Anticorps Monoclonal anti-CD11a

CD11a Monoclonal Antibody for FC

Hôte / Isotype

Mouse / IgG1, kappa

Réactivité testée

Humain

Applications

FC

Conjugaison

Cardinal Red™ Fluorescent Dye

CloneNo.

TS2/4

N° de cat : CR-65194

Synonymes

CD11A, Integrin alpha L, ITGAL, LFA 1, LFA 1A, LFA1A



Applications testées

Résultats positifs en cytométrieCMSP humaines,

Dilution recommandée

ApplicationDilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 μl per 10^6 cells in a 100 µl suspension or 5 μl per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CR-65194 cible CD11a dans les applications de FC et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Mouse / IgG1, kappa
Clonalité Monoclonal
Type Anticorps
Immunogène Lignée de CTL HLA-DR
Nom complet integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
Masse moléculaire calculée 129 kDa
Numéro d’acquisition GenBankBC008777
Symbole du gène ITGAL
Identification du gène (NCBI) 3683
Conjugaison Cardinal Red™ Fluorescent Dye
Excitation/Emission maxima wavelengths592 nm / 611 nm
Forme Liquide
Méthode de purification Purification par protéine G
Tampon de stockage PBS with 0.09% sodium azide and 0.5% BSA.
Conditions de stockageStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160).

Protocole

Product Specific Protocols
FC protocol for Cardinal Red™ CD11a antibody CR-65194Download protocol
Standard Protocols
Click here to view our Standard Protocols