Anticorps Monoclonal anti-CD11a
CD11a Monoclonal Antibody for FC
Hôte / Isotype
Mouse / IgG1, kappa
Réactivité testée
Humain
Applications
FC
Conjugaison
Cardinal Red™ Fluorescent Dye
CloneNo.
TS2/4
N° de cat : CR-65194
Synonymes
Galerie de données de validation
Applications testées
Résultats positifs en cytométrie | CMSP humaines, |
Dilution recommandée
Application | Dilution |
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This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 μl per 10^6 cells in a 100 µl suspension or 5 μl per 100 µl of whole blood. | |
Sample-dependent, check data in validation data gallery |
Informations sur le produit
CR-65194 cible CD11a dans les applications de FC et montre une réactivité avec des échantillons Humain
Réactivité | Humain |
Hôte / Isotype | Mouse / IgG1, kappa |
Clonalité | Monoclonal |
Type | Anticorps |
Immunogène | Lignée de CTL HLA-DR |
Nom complet | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
Masse moléculaire calculée | 129 kDa |
Numéro d’acquisition GenBank | BC008777 |
Symbole du gène | ITGAL |
Identification du gène (NCBI) | 3683 |
Conjugaison | Cardinal Red™ Fluorescent Dye |
Excitation/Emission maxima wavelengths | 592 nm / 611 nm |
Forme | Liquide |
Méthode de purification | Purification par protéine G |
Tampon de stockage | PBS with 0.09% sodium azide and 0.5% BSA. |
Conditions de stockage | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Informations générales
CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160).
Protocole
Product Specific Protocols | |
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FC protocol for Cardinal Red™ CD11a antibody CR-65194 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |