Anticorps Monoclonal anti-CD11a

CD11a Monoclonal Antibody for FC

Hôte / Isotype

Rat / IgG2a, kappa

Réactivité testée

souris

Applications

FC

Conjugaison

Atlantic Blue™ Fluorescent Dye

CloneNo.

M17/4

N° de cat : AB-65177

Synonymes

Cd11a, integrin alpha L, Itgal, LFA 1, Ly 15, Ly 21

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Galerie de données de validation

• 

  FC experiment of mouse splenocytes using AB-65177

  1X10^6 mouse splenocytes were surface stained with 0.5 ug Atlantic Blue™ Anti-Mouse CD11a (AB-65177, Clone: M17/4) (red) or 0.5 ug Control Antibody. Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: splénocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

AB-65177 cible CD11a dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Rat / IgG2a, kappa
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Lymphocytes T cytotoxiques secondaires spléniques de souris C57BL/6
• Nom complet: integrin alpha L
• Numéro d’acquisition GenBank: BC145802
• Symbole du gène: Itgal
• Identification du gène (NCBI): 16408
• Conjugaison: Atlantic Blue™ Fluorescent Dye
• Excitation/Emission maxima wavelengths: 404 nm / 458 nm
• Forme: Liquide
• Méthode de purification: Purifié par chromatographie d'affinité par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide.
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160).