Anticorps Monoclonal anti-CD107b / LAMP2
CD107b / LAMP2 Monoclonal Antibody for FC (Intra)
Hôte / Isotype
Mouse / IgG1
Réactivité testée
Humain
Applications
FC (Intra)
Conjugaison
CoraLite® Plus 405 Fluorescent Dye
CloneNo.
H4B4
N° de cat : CL405-65053
Synonymes
Galerie de données de validation
Applications testées
Résultats positifs en cytométrie | cellules HeLa |
Dilution recommandée
Application | Dilution |
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This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 μl per 10^6 cells in a 100 µl suspension or 5 μl per 100 µl of whole blood. | |
Sample-dependent, check data in validation data gallery |
Informations sur le produit
CL405-65053 cible CD107b / LAMP2 dans les applications de FC (Intra) et montre une réactivité avec des échantillons Humain
Réactivité | Humain |
Hôte / Isotype | Mouse / IgG1 |
Clonalité | Monoclonal |
Type | Anticorps |
Immunogène | Cellules adhérentes humaines de sang périphérique |
Nom complet | lysosomal-associated membrane protein 2 |
Masse moléculaire calculée | 45 kDa |
Numéro d’acquisition GenBank | BC002965 |
Symbole du gène | LAMP2 |
Identification du gène (NCBI) | 3920 |
Conjugaison | CoraLite® Plus 405 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 399 nm / 422 nm |
Forme | Liquide |
Méthode de purification | Purification par protéine G |
Tampon de stockage | PBS with 0.09% sodium azide and 0.5% BSA. |
Conditions de stockage | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Informations générales
LAMP2 (CD107b) is a Lysosomal membrane glycoprotein. LAMP2 is extensively glycosylated with asparagine-linked oligosaccharides which protect it from intracellular proteolysis (PMID: 10521503). Although LAMP-2 is localized primarily in the endosome-lysosomal membrane of cells, it is also found on the plasma membrane under certain circumstances, e.g., after platelet activation, during granulocytic differentiation and activation, and in some tumor cells (PMID: 12221139). LAMP is involved in lysosomal stability and autophagy (PMID: 12221139). This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may plays a role in tumor cell metastasis (PMID 9426697).
Protocole
Product Specific Protocols | |
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FC protocol for CL Plus 405 CD107b / LAMP2 antibody CL405-65053 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |