Anticorps Monoclonal anti-Arginase-1
Arginase-1 Monoclonal Antibody for IF
Hôte / Isotype
Mouse / IgG1
Réactivité testée
Humain, porc, rat, souris
Applications
IF
Conjugaison
CoraLite®594 Fluorescent Dye
CloneNo.
5D6D12
N° de cat : CL594-66129
Synonymes
Galerie de données de validation
Applications testées
Résultats positifs en IF | cellules HepG2, |
Dilution recommandée
Application | Dilution |
---|---|
Immunofluorescence (IF) | IF : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Applications publiées
IF | See 1 publications below |
Informations sur le produit
CL594-66129 cible Arginase-1 dans les applications de IF et montre une réactivité avec des échantillons Humain, porc, rat, souris
Réactivité | Humain, porc, rat, souris |
Réactivité citée | Humain |
Hôte / Isotype | Mouse / IgG1 |
Clonalité | Monoclonal |
Type | Anticorps |
Immunogène | Arginase-1 Protéine recombinante Ag8810 |
Nom complet | arginase, liver |
Masse moléculaire calculée | 236aa,25 kDa; 322aa,35 kDa |
Numéro d’acquisition GenBank | BC005321 |
Symbole du gène | ARG1 |
Identification du gène (NCBI) | 383 |
Conjugaison | CoraLite®594 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 588 nm / 604 nm |
Forme | Liquide |
Méthode de purification | Purification par protéine G |
Tampon de stockage | PBS avec glycérol à 50 %, Proclin300 à 0,05 % et BSA à 0,5 %, pH 7,3. |
Conditions de stockage | Stocker à -20 °C. Éviter toute exposition à la lumière. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. |
Informations générales
Arginase-1 (Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemical marker of hepatocellular differentiation in fine needle aspiration cytology and a marker of hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation(PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia (ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control.(PMID:27117406). ARG1 is a novel biomarker of post-stroke immune suppression(2016). The antibody is conjugated with CL594, Ex/Em 593 nm/614 nm.
Protocole
Product Specific Protocols | |
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IF protocol for CL594 Arginase-1 antibody CL594-66129 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
Publications
Species | Application | Title |
---|---|---|
Adv Sci (Weinh) Wireless Localized Electrical Stimulation Generated by an Ultrasound-Driven Piezoelectric Discharge Regulates Proinflammatory Macrophage Polarization. |
Avis
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
FH Rachel (Verified Customer) (08-09-2022) | This ab works really well for IF in murine liver samples (formalin-fixed).
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