Anticorps Monoclonal anti-ALCAM

ALCAM Monoclonal Antibody for FC

Hôte / Isotype

Mouse / IgG1, kappa

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

3A6

N° de cat : 65223-1-Ig

Synonymes

ALCAM, CD166, CD166 antigen, FLJ38514, MEMD

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Galerie de données de validation

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  FC experiment of human PBMCs using 65223-1-Ig

  1X10^6 PHA treated human PBMCs were surface stained with 0.2 ug Anti-Human ALCAM (65223-1-Ig, Clone:3A6) and CL594-Goat anti-Mouse IgG at dilution 1:1000 (red) or unstained (blue). Cells were not fixed. Monocytes were gated.

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Applications testées

• Résultats positifs en cytométrie: PHA treated human PBMCs,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

65223-1-Ig cible ALCAM dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1, kappa
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Cultured human thymic epithelial cells
• Nom complet: activated leukocyte cell adhesion molecule
• Masse moléculaire calculée: 105 kDa
• Numéro d’acquisition GenBank: BC057809
• Symbole du gène: ALCAM
• Identification du gène (NCBI): 214
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité
• Tampon de stockage: PBS with 0.09% sodium azide.
• Conditions de stockage: Store at 2-8°C. Stable for one year after shipment.

Informations générales

Activated leukocyte cell adhesion molecule (ALCAM, also known as CD166) is a cell adhesion molecule that belongs to the immunoglobulin superfamily. It is involved in cell-cell adhesion through homophilic and heterophilic (to CD6) interactions. ALCAM is widely expressed in a variety of normal tissues and cell types, including activated T cells and monocytes, epithelial cells, fibroblasts, neuronal cells, hepatocytes, and bone marrow mesenchymal stem cells (PMID: 7760007; 25221999). Altered ALCAM expression has been associated with the differentiation state and progression in some neoplasms including melanoma, prostate, colorectal, and breast cancers (PMID: 20461761; 18172759).