VLDLR Polyklonaler Antikörper

VLDLR Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte und mehr (1)

Anwendung

WB, IF, ELISA

Konjugation

Unkonjugiert

Publikationen

7

Kat-Nr. : 19493-1-AP

Synonyme

CHRMQ1, VLDL R, VLDL receptor, VLDLR, VLDLRCH

---

Galerie der Validierungsdaten

• 

  WB analysis using 19493-1-AP

  MCF-7 cells were subjected to SDS PAGE followed by western blot with 19493-1-AP (VLDLR antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse ovary using 19493-1-AP

  mouse ovary tissue were subjected to SDS PAGE followed by western blot with 19493-1-AP (VLDLR antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: MCF-7-Zellen, Maus-Eierstockgewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 1 publications below
• WB: See 7 publications below
• IF: See 1 publications below

Produktinformation

19493-1-AP bindet in WB, IF, ELISA VLDLR und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human, Maus, Ratte, Zebrafisch
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: very low density lipoprotein receptor
• Berechnetes Molekulargewicht: 96 kDa
• Beobachtetes Molekulargewicht: 96 kDa, 160 kDa
• GenBank-Zugangsnummer: NM_003383
• Gene symbol: VLDLR
• Gene ID (NCBI): 7436
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

VLDLR binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. VLDLR binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (cytoplasmic domain of low-density lipoprotein receptor). For glycosylated, the MW of VLDLR migrates to ~160kd.

Publikationen

Species	Application	Title
zebrafish	WB	Neuron; Molecular microcircuitry underlies functional specification in a basal ganglia circuit dedicated to vocal learning.; Authors - Hilliard Austin T AT
mouse	WB	Food Funct; Monounsaturated fatty acid-enriched olive oil exacerbates chronic alcohol-induced hepatic steatosis and liver injury in C57BL/6J mice; Authors - Rui Guo
rat	WB	Front Pharmacol; Protective Effect of Patchouli Alcohol Against High-Fat Diet Induced Hepatic Steatosis by Alleviating Endoplasmic Reticulum Stress and Regulating VLDL Metabolism in Rats.; Authors - Xue Wu
mouse	WB	PLoS One; Gut microbiota and butyrate contribute to nonalcoholic fatty liver disease in premenopause due to estrogen deficiency.; Authors - Limin Liu
mouse	WB	Front Nutr; Dietary camellia seed oil attenuates liver injury in mice chronically exposed to alcohol; Authors - Rui Guo
human	WB,IF	Front Oncol; VLDLR disturbs quiescence of breast cancer stem cells in a ligand-independent function; Authors - Mengying Yang ; KD Validated