UGT1A1 Polyklonaler Antikörper

UGT1A1 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus und mehr (1)

Anwendung

WB, IHC, IF, ELISA

Konjugation

Unkonjugiert

Publikationen

7

Kat-Nr. : 23495-1-AP

Synonyme

GNT1, HUG BR1, UDPGT, UDPGT 1 1, UGT 1A, UGT1, UGT1 01, UGT1*1, UGT1.1, UGT1A, UGT1A1

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Galerie der Validierungsdaten

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  WB analysis using 23495-1-AP

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 23495-1-AP (UGT1A1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Mauslebergewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 6 publications below
• IHC: See 2 publications below
• IF: See 2 publications below

Produktinformation

23495-1-AP bindet in WB, IHC, IF, ELISA UGT1A1 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: UGT1A1 fusion protein Ag19001
• Vollständiger Name: UDP glucuronosyltransferase 1 family, polypeptide A1
• Berechnetes Molekulargewicht: 533 aa, 60 kDa
• Beobachtetes Molekulargewicht: 50-60 kDa, 65-70 kDa
• GenBank-Zugangsnummer: BC128415
• Gene symbol: UGT1A1
• Gene ID (NCBI): 54658
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-affinitätsgereinigt
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

UDP-glucuronosyltransferase 1A1 (UGT1A1) is one of nine transferases encoded on the UGT1 locus. Developmental regulation of the UGT1A1 gene is an important process that is needed to achieve normal levels of serum total bilirubin (TB). UGT1A1 is a 50-60 kda member of the UGT1A subfamily, and can be detected as 65-70kda band after posttranslational modification.

Publikationen

Species	Application	Title
human	WB,IF	J Mol Biol; Silencing of Aberrant Secretory Protein Expression by Disease-Associated Mutations.; Authors - Elena B Tikhonova
rat	WB,IHC	Phytomedicine; Oleanolic acid alleviates ANIT-induced cholestatic liver injury by activating Fxr and Nrf2 pathways to ameliorate disordered bile acids homeostasis.; Authors - Jianming Liu
human,rat	WB,IHC	Phytomedicine; NRF2 and FXR dual signaling pathways cooperatively regulate the effects of oleanolic acid on cholestatic liver injury; Authors - Jianming Liu
mouse	WB	Front Nutr; The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism.; Authors - Canxia He
human	WB	Metabolites; The Glycosyltransferase Pathway: An Integrated Analysis of the Cell Metabolome; Authors - Yannick Audet-Delage
mouse	WB	Front Pharmacol; Bicyclol attenuates high fat diet-induced non-alcoholic fatty liver disease/non-alcoholic steatohepatitis through modulating multiple pathways in mice; Authors - Jingyi Wu