TOM1 Polyklonaler Antikörper

TOM1 Polyklonal Antikörper für WB,ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF,ELISA

Konjugation

Unkonjugiert

Publikationen

1

Kat-Nr. : 17506-1-AP

Synonyme

Target of Myb protein 1, target of myb1 (chicken), TOM1

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Galerie der Validierungsdaten

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  WB analysis of human liver using 17506-1-AP

  human liver tissue were subjected to SDS PAGE followed by western blot with 17506-1-AP (TOM1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

• 

  WB analysis of human skeletal muscle using 17506-1-AP

  human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 17506-1-AP (TOM1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

• 

  WB analysis of K-562 using 17506-1-AP

  K-562 cells were subjected to SDS PAGE followed by western blot with 17506-1-AP (TOM1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

• 

  WB analysis of HeLa using 17506-1-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 17506-1-AP (TOM1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: humanes Lebergewebe, HeLa-Zellen, humanes Skelettmuskelgewebe, K-562-Zellen, L02-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:3000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• IHC: See 1 publications below
• IF: See 1 publications below

Produktinformation

17506-1-AP bindet in WB, IHC, IF,ELISA TOM1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: TOM1 fusion protein Ag11706
• Vollständiger Name: target of myb1 (chicken)
• Berechnetes Molekulargewicht: 493 aa, 54 kDa
• Beobachtetes Molekulargewicht: 54 kDa
• GenBank-Zugangsnummer: BC046151
• Gene symbol: TOM1
• Gene ID (NCBI): 10043
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TOM1 is a member of VHS (VPS-27, Hrs, and STAM)-domain-containing protein family that functions as adaptor proteins in the intracellular trafficking and sorting of plasma membrane proteins. TOM1 colocalized with key proteins of the protein-degradation systems. Recently TOM1 has been reported to be localized in the hallmarks of AD pathology (27206884).

Publikationen

Species	Application	Title
human	IHC,IF	J Neurol Sci; Immunolocalization of Tom1 in relation to protein degradation systems in Alzheimer's disease.; Authors - Kouki Makioka